engleski

Sleep architecture in severe OSA patients

This study was performed to investigate sleep architecture, and distribution of alpha brain activity and sleep spindles in severe OSA patients.Polysomnographic data of 99 patients with OSA referred to Split Sleep Medical Center in Split, Croatia, EU, were analyzed for parameters including sleep duration, percentage and duration of sleep stages N1, N2, N3 and REM, count of alpha and spindles in N2 according to Neuro Report on Alice 5 device. Two groups of OSA patients with no other comorbidities (OSA-nocm) were compared: severe OSA-nocm (N=31), and mild OSA-nocm (N=8). Additionally, group of severe OSA patients with comorbidities (hypertension and/or diabetes mellitus, OSA-hdm, N=60) was analyzed and compared to severe OSA-nocm group.Decreased amount of N3 sleep stage and increased alpha activity during N2 sleep stage indicated impaired sleep architecture and non-restorative sleep in severe OSA patients, accentuating the effects of OSA on sleep architecture.

sleep architecture, OSA, sleep stages

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