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Pregled bibliografske jedinice broj: 1153397

Immunoglobulin G Glycosylation in Diseases


Marija Pezer
Immunoglobulin G Glycosylation in Diseases // Antibody Glycosylation / Pezer, Marija (ur.).
Cham: Springer, 2021. str. 395-431 doi:10.1007/978-3-030-76912-3_13


CROSBI ID: 1153397 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Immunoglobulin G Glycosylation in Diseases

Autori
Marija Pezer

Vrsta, podvrsta i kategorija rada
Poglavlja u knjigama, pregledni

Knjiga
Antibody Glycosylation

Urednik/ci
Pezer, Marija

Izdavač
Springer

Grad
Cham

Godina
2021

Raspon stranica
395-431

ISBN
978-3-030-76911-6

Ključne riječi
IgG glycosylation ; differential glycosylation ; disease ; biomarker

Sažetak
Changes in immunoglobulin G (IgG) glycosylation pattern have been observed in a vast array of auto- and alloimmune, infectious, cardiometabolic, malignant, and other diseases. This chapter contains an updated catalog of over 140 studies within which IgG glycosylation analysis was performed in a disease setting. Since the composition of IgG glycans is known to modulate its effector functions, it is suggested that a changed IgG glycosylation pattern in patients might be involved in disease development and progression, representing a predisposition and/or a functional effector in disease pathology. In contrast to the glycopattern of bulk serum IgG, which likely relates to the systemic inflammatory background, the glycosylation profile of antigen- specific IgG probably plays a direct role in disease pathology in several infectious and allo- and autoimmune antibody-dependent diseases. Depending on the specifics of any given disease, IgG glycosylation read-out might therefore in the future be developed into a useful clinical biomarker, or a supplementary to currently used biomarkers.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Temeljne medicinske znanosti



POVEZANOST RADA


Projekti:
EK-EFRR-KK.01.2.2.03.0006 - Centar kompetencija u molekularnoj dijagnostici (CEKOM) (Knjaz, Damir; Lauc, Gordan; Vugrek, Oliver; Polašek, Ozren, EK - KK.01.2.2.03) ( POIROT)

Ustanove:
GENOS d.o.o.

Profili:

Avatar Url Marija Pezer (autor)

Poveznice na cjeloviti tekst rada:

doi link.springer.com

Citiraj ovu publikaciju:

Marija Pezer
Immunoglobulin G Glycosylation in Diseases // Antibody Glycosylation / Pezer, Marija (ur.).
Cham: Springer, 2021. str. 395-431 doi:10.1007/978-3-030-76912-3_13
Marija Pezer (2021) Immunoglobulin G Glycosylation in Diseases. U: Pezer, M. (ur.) Antibody Glycosylation. Cham, Springer, str. 395-431 doi:10.1007/978-3-030-76912-3_13.
@inbook{inbook, editor = {Pezer, M.}, year = {2021}, pages = {395-431}, DOI = {10.1007/978-3-030-76912-3\_13}, keywords = {IgG glycosylation, differential glycosylation, disease, biomarker}, doi = {10.1007/978-3-030-76912-3\_13}, isbn = {978-3-030-76911-6}, title = {Immunoglobulin G Glycosylation in Diseases}, keyword = {IgG glycosylation, differential glycosylation, disease, biomarker}, publisher = {Springer}, publisherplace = {Cham} }
@inbook{inbook, editor = {Pezer, M.}, year = {2021}, pages = {395-431}, DOI = {10.1007/978-3-030-76912-3\_13}, keywords = {IgG glycosylation, differential glycosylation, disease, biomarker}, doi = {10.1007/978-3-030-76912-3\_13}, isbn = {978-3-030-76911-6}, title = {Immunoglobulin G Glycosylation in Diseases}, keyword = {IgG glycosylation, differential glycosylation, disease, biomarker}, publisher = {Springer}, publisherplace = {Cham} }

Citati:





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