The Effect of Micromixer Geometry on the Diameters of Emulsion Droplets: NIR Spectroscopy and Artificial Neural Networks Modeling (CROSBI ID 708609)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Jurina, Tamara ; Čulo, Ivana ; Benković, Maja ; Gajdoš Kljusurić, Jasenka ; Valinger, Davor ; Jurinjak Tušek, Ana
engleski
The Effect of Micromixer Geometry on the Diameters of Emulsion Droplets: NIR Spectroscopy and Artificial Neural Networks Modeling
In this work, teardrop micromixer and swirl micromixer were used for preparation of oil- in-water (O/W) emulsions with Tween 20 and PEG 2000 as emulsifiers (concentrations: 2% and 4%) at different total flow rates (20–280 μL/min). Stability of the prepared O/W emulsions was evaluated based on the droplet size of the dispersed phase. For determination of the droplet size, the average Feret diameter was used. Furthermore, near infrared (NIR) spectra of all prepared samples were collected. Obtained results showed that the change in the droplet size followed the same trend for both micromixers used in the experiment. At higher total flow rates, emulsification resulted in smaller values of the average Feret diameter. Values of the average Feret diameter were higher for emulsions prepared in the swirl micromixer, compared to the teardrop micromixer. Artificial Neural Network (ANNs) models, based on the recorded NIR spectra of emulsions, were developed to predict the droplet size of the dispersed phase. The obtained ANN models have high values of R2 for training, test, and validation, with small error values and show that NIR spectroscopy, in combination with ANNs, could be efficiently used for evaluation of the stability of oil-in-water emulsions.
micromixer geometry ; average feret diameter ; oil in water emulsions ; artificial neural network models ; NIR spectra
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Podaci o prilogu
26-26.
2021.
objavljeno
10.3390/Micromachines2021-09658
Podaci o matičnoj publikaciji
Engineering Proceedings- Proceedings of The 1st International Conference on Micromachines and Applications)
Stiharu, Ion
Basel: MDPI Books
2673-4591
Podaci o skupu
1st International Conference on Micromachines and Applications (ICMA 2021)
poster
15.04.2021-30.04.2021
Basel, Švicarska; online