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Community‐based pharmacists' role in deprescribing: a systematic review (CROSBI ID 298698)

Prilog u časopisu | pregledni rad (znanstveni) | međunarodna recenzija

Bužančić, Iva ; Kummer, Ingrid ; Držaić, Margita ; Ortner Hadžiabdić, Maja Community‐based pharmacists' role in deprescribing: a systematic review // British journal of clinical pharmacology, 88 (2022), 2; 452-463. doi: 10.1111/bcp.14947

Podaci o odgovornosti

Bužančić, Iva ; Kummer, Ingrid ; Držaić, Margita ; Ortner Hadžiabdić, Maja

engleski

Community‐based pharmacists' role in deprescribing: a systematic review

Community-based pharmacists are important stakeholders in providing continuing care for chronic multi-morbid patients, and their role is steadily expanding. The aim of this study is to examine the literature exploring community-based pharmacist-initiated and/or -led deprescribing and to evaluate the impact on the success of deprescribing and clinical outcomes. Methods Library and clinical trials databases were searched from inception to March 2020. Studies were included if they explored deprescribing in adults, by community-based pharmacists and were available in English. Two reviewers extracted data independently using a pre-agreed data extraction template. Meta-analysis was not performed due to heterogeneity of study designs, types of intervention and outcomes. Results A total of 24 studies were included in the review. Results were grouped based on intervention method into four categories: educational interventions ; interventions involving medication review, consultation or therapy management ; pre-defined pharmacist-led deprescribing interventions ; and pharmacist-led collaborative interventions. All types of interventions resulted in greater discontinuation of medications in comparison to usual care. Educational interventions reported financial benefits as well. Medication review by community- based pharmacist can lead to successful deprescribing of high-risk medication, but do not affect the risk or rate of falls, rate of hospitalisations, mortality or quality of life. Pharmacist-led medication review, in patients with mental illness, resulting in deprescribing improves anticholinergic side effects, memory and quality of life. Pre-defined pharmacist-led deprescribing did not reduce healthcare resource consumptions but can contribute to financial savings. Short follow-up periods prevent evaluation of long-term sustainability of deprescribing interventions. Conclusion This systematic review suggests community-based pharmacists can lead deprescribing interventions and that they are valuable partners in deprescribing collaborations, providing necessary monitoring throughout tapering and post-follow-up to ensure the success of an intervention.

deprescribing ; systematic review ; community pharmacist

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Podaci o izdanju

88 (2)

2022.

452-463

objavljeno

0306-5251

10.1111/bcp.14947

Povezanost rada

Farmacija

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