Conservation genomic analyses of two Croatian autochthonous sheep breeds (CROSBI ID 707189)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Spehar, Marija ; Ferenčaković, Maja ; Čurik, Ino ; Karapandža, Nina ; Barać, Zdravko ; Sinković, Tanja ; CubricCurik, Vlatka
engleski
Conservation genomic analyses of two Croatian autochthonous sheep breeds
Istrian (IS) and Pag (PS) sheep breeds are Croatian autochthonous sheep breeds. We analyzed genotypes of 175 animals (96 IS, and 75 PS) using Illumina OvineSNP50 BeadChip array and estimated genomic inbreeding levels (FROH) and linkage disequilibrium effective population size (NeLD). We also defined the genomic position of IS and PS concerning overall 671 animals of 22 Italian, Spanish and some Merino sheep breeds. For this purpose, we used publicly available data from Dryad digital repository. The inbreeding level based on runs of homozygosity (FROH) was higher in IS compared to PS for FROH>2Mb, 0.08 vs. 0.04, FROH>8Mb, 0.04 vs. 0.03, and FROH>16Mb, 0.02 vs. 0.01 respectively. Software NeEstimator was used to estimate Ne from the parental generation of the sample based on the linkage disequilibrium (LD) method. Estimated NeLD for IS was 101 (95% CI= 81-130), while higher NeLD of 222 (95% CI= 161-343) was obtained for PS. Principal Components Analysis of the overall dataset showed separation of both, IS and PS from other breeds. However, PS was placed near to the cluster containing some Italian breeds (Massese, Appenninica, Sardinian White, Comisana, Leccese, and Laticauda) while IS was slightly remote. To our knowledge, this is the first genomic analysis of IS and PS providing valuable insights into their conservation status.
sheep ; autochthonous breeds ; genomic inbreeding ; LD effective population size
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Podaci o prilogu
111-111.
2019.
objavljeno
10.3920/978-90-8686-890-2
Podaci o matičnoj publikaciji
Wageningen: Wageningen Academic Publishers
978-90-8686-339-6
1382-6077
Podaci o skupu
70th annual meeting of the European Federation of Animal Science
predavanje
26.08.2019-30.08.2019
Gent, Belgija