Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 1141016

Preparation of multifunctional N-doped carbon quantum dots from citrus clementina peel: investigating targeted pharmacological activities and the potential application for Fe3+ sensing


Šafranko, Silvija; Stanković, Anamarija; Hajra, Sugato; Kim, Hoe Joon; Strelec, Ivica; Dutour-Sikirić, Maja; Weber, Igor; Herak Bosnar, Maja; Grbčić, Petra; Kraljević Pavelić, Sandra et al.
Preparation of multifunctional N-doped carbon quantum dots from citrus clementina peel: investigating targeted pharmacological activities and the potential application for Fe3+ sensing // Pharmaceuticals, 14 (2021), 9; 857, 18 doi:10.3390/ph14090857 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1141016 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Preparation of multifunctional N-doped carbon quantum dots from citrus clementina peel: investigating targeted pharmacological activities and the potential application for Fe3+ sensing

Autori
Šafranko, Silvija ; Stanković, Anamarija ; Hajra, Sugato ; Kim, Hoe Joon ; Strelec, Ivica ; Dutour-Sikirić, Maja ; Weber, Igor ; Herak Bosnar, Maja ; Grbčić, Petra ; Kraljević Pavelić, Sandra ; Széchenyi, Aleksandar ; Mishra, Yogendra Kumar ; Jerković, Igor ; Jokić, Stela

Izvornik
Pharmaceuticals (1424-8247) 14 (2021), 9; 857, 18

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
citrus waste ; carbon quantum dots ; N-doping ; Fe3+ detection ; biocompatibility

Sažetak
Carbon quantum dots (CQDs) have recently emerged as innovative theranostic nanomaterials, enabling fast and effective diagnosis and treatment. In this study, a facile hydrothermal approach for N- doped biomass-derived CQDs preparation from Citrus clementina peel and amino acids glycine (Gly) and arginine (Arg) has been presented. The gradual increase in the N-dopant (amino acids) nitrogen content increased the quantum yield of synthesized CQDs. The prepared CQDs exhibited good biocompatibility, stability in aqueous, and high ionic strength media, similar optical properties, while differences were observed regarding the structural and chemical diversity, and biological and antioxidant activity. The antiproliferative effect of CQD@Gly against pancreatic cancer cell lines (CFPAC-1) was observed. At the same time, CQD@Arg has demonstrated the highest quantum yield and antioxidant activity by DPPH scavenging radical method of 81.39 ± 0.39% and has been further used for the ion sensing and cellular imaging of cancer cells. The obtained results have demonstrated selective response toward Fe3+ detection, with linear response ranging from 7.0 µmol dm−3 to 50.0 µmol dm−3 with R2 = 0.9931 and limit of detection (LOD) of 4.57 ± 0.27 µmol dm−3. This research could be a good example of sustainable biomass waste utilization with potential for biomedical analysis and ion sensing applications.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Interdisciplinarne prirodne znanosti, Farmacija



POVEZANOST RADA


Projekti:
HRZZ-UIP-2017-05-9909 - Primjena inovativnih tehnika ekstrakcije bioaktivnih komponenti iz nusproizvoda biljnoga podrijetla (ByProExtract) (Jokić, Stela, HRZZ - 2017-05) ( POIROT)
EK-KF-KK.01.1.1.01.0002 - Bioprospecting Jadranskog mora (Čož-Rakovac, Rozelinda; Dragović-Uzelac, Verica; Šantek, Božidar; Jokić, Stela; Jerković, Igor; Kraljević Pavelić, Sandra, EK - KK.01.1.1.01) ( POIROT)

Ustanove:
Kemijsko-tehnološki fakultet, Split,
Institut "Ruđer Bošković", Zagreb,
Prehrambeno-tehnološki fakultet, Osijek,
Sveučilište u Osijeku - Odjel za kemiju,
Sveučilište u Rijeci - Odjel za biotehnologiju,
Fakultet zdravstvenih studija u Rijeci

Poveznice na cjeloviti tekst rada:

doi www.mdpi.com fulir.irb.hr

Citiraj ovu publikaciju:

Šafranko, Silvija; Stanković, Anamarija; Hajra, Sugato; Kim, Hoe Joon; Strelec, Ivica; Dutour-Sikirić, Maja; Weber, Igor; Herak Bosnar, Maja; Grbčić, Petra; Kraljević Pavelić, Sandra et al.
Preparation of multifunctional N-doped carbon quantum dots from citrus clementina peel: investigating targeted pharmacological activities and the potential application for Fe3+ sensing // Pharmaceuticals, 14 (2021), 9; 857, 18 doi:10.3390/ph14090857 (međunarodna recenzija, članak, znanstveni)
Šafranko, S., Stanković, A., Hajra, S., Kim, H., Strelec, I., Dutour-Sikirić, M., Weber, I., Herak Bosnar, M., Grbčić, P. & Kraljević Pavelić, S. (2021) Preparation of multifunctional N-doped carbon quantum dots from citrus clementina peel: investigating targeted pharmacological activities and the potential application for Fe3+ sensing. Pharmaceuticals, 14 (9), 857, 18 doi:10.3390/ph14090857.
@article{article, author = {\v{S}afranko, Silvija and Stankovi\'{c}, Anamarija and Hajra, Sugato and Kim, Hoe Joon and Strelec, Ivica and Dutour-Sikiri\'{c}, Maja and Weber, Igor and Herak Bosnar, Maja and Grb\v{c}i\'{c}, Petra and Kraljevi\'{c} Paveli\'{c}, Sandra and Sz\'{e}chenyi, Aleksandar and Mishra, Yogendra Kumar and Jerkovi\'{c}, Igor and Joki\'{c}, Stela}, year = {2021}, pages = {18}, DOI = {10.3390/ph14090857}, chapter = {857}, keywords = {citrus waste, carbon quantum dots, N-doping, Fe3+ detection, biocompatibility}, journal = {Pharmaceuticals}, doi = {10.3390/ph14090857}, volume = {14}, number = {9}, issn = {1424-8247}, title = {Preparation of multifunctional N-doped carbon quantum dots from citrus clementina peel: investigating targeted pharmacological activities and the potential application for Fe3+ sensing}, keyword = {citrus waste, carbon quantum dots, N-doping, Fe3+ detection, biocompatibility}, chapternumber = {857} }
@article{article, author = {\v{S}afranko, Silvija and Stankovi\'{c}, Anamarija and Hajra, Sugato and Kim, Hoe Joon and Strelec, Ivica and Dutour-Sikiri\'{c}, Maja and Weber, Igor and Herak Bosnar, Maja and Grb\v{c}i\'{c}, Petra and Kraljevi\'{c} Paveli\'{c}, Sandra and Sz\'{e}chenyi, Aleksandar and Mishra, Yogendra Kumar and Jerkovi\'{c}, Igor and Joki\'{c}, Stela}, year = {2021}, pages = {18}, DOI = {10.3390/ph14090857}, chapter = {857}, keywords = {citrus waste, carbon quantum dots, N-doping, Fe3+ detection, biocompatibility}, journal = {Pharmaceuticals}, doi = {10.3390/ph14090857}, volume = {14}, number = {9}, issn = {1424-8247}, title = {Preparation of multifunctional N-doped carbon quantum dots from citrus clementina peel: investigating targeted pharmacological activities and the potential application for Fe3+ sensing}, keyword = {citrus waste, carbon quantum dots, N-doping, Fe3+ detection, biocompatibility}, chapternumber = {857} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


Citati:





    Contrast
    Increase Font
    Decrease Font
    Dyslexic Font