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Pregled bibliografske jedinice broj: 1140541

Comparison of gastrointestinal stability of isothiocyanates from Tropaeolum majus L. altum using in vitro and ex vivo digestion methods


Vrca, Ivana; Burčul, Franko; Blažević, Ivica; Bratanić, Andre; Bilušić, Tea
Comparison of gastrointestinal stability of isothiocyanates from Tropaeolum majus L. altum using in vitro and ex vivo digestion methods // Croatian Journal of Food Science and Technology (2021) doi:10.17508/CJFST.2021.13.2.04 (stručni, prihvaćen)


CROSBI ID: 1140541 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Comparison of gastrointestinal stability of isothiocyanates from Tropaeolum majus L. altum using in vitro and ex vivo digestion methods

Autori
Vrca, Ivana ; Burčul, Franko ; Blažević, Ivica ; Bratanić, Andre ; Bilušić, Tea

Vrsta, podvrsta
Radovi u časopisima, stručni

Izvornik
Croatian Journal of Food Science and Technology (2021)

Status rada
Prihvaćen

Ključne riječi
Tropaeolum majus L. ; benzyl isothiocyanate ; gastrointestinal stability ; in vitro digestion method ; ex vivo digestion method

Sažetak
Tropaeolum majus L. is an annual herbaceous plant and a member of the Tropaeolaceae family which belongs to the Brassicales order. It is an excellent source of flavonoids, carotenoids, phenolic acids, vitamin C, and is a plant that contains glucosinolate glucotropaeolin. The major degradation product of glucotropaeolin is benzyl isothiocyanate which is known for its various biological activities. In this study, an essential oil was isolated from the seeds of the Tropaeolum majus L. altum plant by microwave-assisted distillation and analyzed using GC-MS technique. Two compounds were identified, benzyl isothiocyanate as the major one (97.81%), and 2-phenylacetonitrile as a minor one (0.80%). Tropaeolum majus L. altum essential oil and pure benzyl isothiocyanate were then submitted to the two-phase in vitro and ex vivo digestion simulations. The analysis performed by GC-MS/MS technique showed greater stability of benzyl isothiocyanate from essential oil after in vitro (97.57%), and ex vivo (73.47%) gastric phases of the simulated digestion methods, compared to its stability after in vitro (71.17%) and ex vivo (54.90%) intestinal phases. Similar trend was shown for pure benzyl isothiocyanate.

Izvorni jezik
Engleski

Znanstvena područja
Kemija, Prehrambena tehnologija



POVEZANOST RADA


Projekti:
HRZZ-IP-2016-06-1316 - Biljke kao izvor bioaktivnih sumporovih spojeva te njihova sposobnost hiperakumulacije metala (BioSMe) (Blažević, Ivica, HRZZ - 2016-06) ( POIROT)

Ustanove:
Kemijsko-tehnološki fakultet, Split

Profili:

Avatar Url Tea Bilušić (autor)

Avatar Url Andre Bratanić (autor)

Avatar Url Ivana Vrca (autor)

Avatar Url Ivica Blažević (autor)

Avatar Url Franko Burčul (autor)

Poveznice na cjeloviti tekst rada:

doi

Citiraj ovu publikaciju:

Vrca, Ivana; Burčul, Franko; Blažević, Ivica; Bratanić, Andre; Bilušić, Tea
Comparison of gastrointestinal stability of isothiocyanates from Tropaeolum majus L. altum using in vitro and ex vivo digestion methods // Croatian Journal of Food Science and Technology (2021) doi:10.17508/CJFST.2021.13.2.04 (stručni, prihvaćen)
Vrca, I., Burčul, F., Blažević, I., Bratanić, A. & Bilušić, T. (2021) Comparison of gastrointestinal stability of isothiocyanates from Tropaeolum majus L. altum using in vitro and ex vivo digestion methods. Prihvaćen za objavljivanje u Croatian Journal of Food Science and Technology. [Preprint] doi:10.17508/CJFST.2021.13.2.04.
@unknown{unknown, author = {Vrca, Ivana and Bur\v{c}ul, Franko and Bla\v{z}evi\'{c}, Ivica and Bratani\'{c}, Andre and Bilu\v{s}i\'{c}, Tea}, year = {2021}, DOI = {10.17508/CJFST.2021.13.2.04}, keywords = {Tropaeolum majus L., benzyl isothiocyanate, gastrointestinal stability, in vitro digestion method, ex vivo digestion method}, journal = {Croatian Journal of Food Science and Technology}, doi = {10.17508/CJFST.2021.13.2.04}, title = {Comparison of gastrointestinal stability of isothiocyanates from Tropaeolum majus L. altum using in vitro and ex vivo digestion methods}, keyword = {Tropaeolum majus L., benzyl isothiocyanate, gastrointestinal stability, in vitro digestion method, ex vivo digestion method} }
@unknown{unknown, author = {Vrca, Ivana and Bur\v{c}ul, Franko and Bla\v{z}evi\'{c}, Ivica and Bratani\'{c}, Andre and Bilu\v{s}i\'{c}, Tea}, year = {2021}, DOI = {10.17508/CJFST.2021.13.2.04}, keywords = {Tropaeolum majus L., benzyl isothiocyanate, gastrointestinal stability, in vitro digestion method, ex vivo digestion method}, journal = {Croatian Journal of Food Science and Technology}, doi = {10.17508/CJFST.2021.13.2.04}, title = {Comparison of gastrointestinal stability of isothiocyanates from Tropaeolum majus L. altum using in vitro and ex vivo digestion methods}, keyword = {Tropaeolum majus L., benzyl isothiocyanate, gastrointestinal stability, in vitro digestion method, ex vivo digestion method} }

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