Comparative analysis of cell wall-related proteins of different yeasts (CROSBI ID 705989)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa
Podaci o odgovornosti
Lozančić, Mateja ; Žunar, Bojan ; Hrestak, Dora ; Lopandić, Ksenija ; Teparić, Renata ; Mrša, Vladimir
engleski
Comparative analysis of cell wall-related proteins of different yeasts
The yeast cell wall is an extracellular structure with a complex role in preserving cell shape and integrity, and in interaction with different molecules and cells in its surrounding. Fact that 1200 Saccharomyces cerevisiae genes directly or indirectly affect cell wall formation and regulation (de Groot et al., 2001) clearly speaks of the importance of the cell wall. Here we present results from our recently published manuscript of in silico analysis comparing 187 S. cerevisiae proteins involved in cell wall biogenesis and function with cell wall proteomes of 92 different yeast species. The main goal of the research was to estimate the evolutionary conservation of proteins involved in protein glycosylation, cell wall synthesis and remodeling, and of cell wall proteins with still unknown functions. As expected, proteins involved in processes of great importance for cell wall integrity and its protective function were highly conserved. However, GPI anchored proteins involved in flocculation, aggregation, cell separation, and those with still unknown functions were not highly conserved. This analysis was coupled with analysis of proteins located in the cell wall by protein biotinylation and western blotting. Results of this analysis show distinctive protein patterns and significant differences in the overall amount of cell wall proteins for different yeast genera, and even for different species of the same genera. de Groot, P.W. et al. 2001. Comp. Funct. Genomics, 2(3), pp.124-142.
Cell wall proteome, yeasts, cell wall protein profiles
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Podaci o prilogu
389-389.
2021.
objavljeno
Podaci o matičnoj publikaciji
ICY15 meets ICYGMB30 Programme & Abstracts
Podaci o skupu
ICY15 meets ICYGMB30: The Spirit of Yeast
poster
23.08.2021-27.08.2021
Beč, Austrija