engleski

Impact of rehabilitation versus edentulism in systemic health and quality of life in patients affected by periodontitis. A systematic review and meta-analysis

Aims: To investigate the effect of rehabilitation in fully/partially edentulous patients with stage IV periodontitis on oral health-related quality of life (OHRQoL) and systemic health. Materials and methods: A systematic electronic and manual search was conducted. Three authors independently reviewed, selected, and extracted data. Outcomes were OHRQoL (Oral Health Impact Profile, OHIP-14 and OHIP-49 ; General Oral Health Assessment Index, GOHAI ; visual analogue scale ; symptoms registration) and systemic health-related outcomes (incidence and prevalence of systemic diseases, values of systemic disease indicators). Qualitative data were synthesised for OHRQoL and systemic health-related outcomes. Meta-analysis was conducted on available quantitative data. Results: The search identified 59 articles (6724 subjects in total). OHRQoL improved across all the studies, irrespective of the number of missing teeth, their location or treatment modality. Meta- analysis showed significant improvement of OHIP-49 (36.86, p<0.01) in manuscripts including periodontitis-affected subjects, consistently with the remaining literature (score points reduction post-rehabilitation OHIP-14=10.52, OHIP-49=56.02, GOHAI=5.40, p<0.01 for all). Non-rehabilitated subjects exhibited inferior cognitive status, higher medication intake and frailty. However, data are limited and should be interpreted with caution. Conclusions: Oral rehabilitation improves OHRQoL and, potentially, systemic health in edentulous patients. It is unclear if these findings may be extrapolated to stage IV periodontitis patients.

periodontitis stage IV ; edentulism ; quality of life ; systemic health

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