The pharmacoeconomic impact of follitropin alpha biosimilars in IVF therapy in Europe: a report of the literature (CROSBI ID 297311)
Prilog u časopisu | pregledni rad (stručni) | međunarodna recenzija
Podaci o odgovornosti
Šprem Goldštajn, Marina ; Mikuš, Mislav ; Ćorić, Mario ; Orešković, Slavko ; Dumančić, Stipe ; Noventa, Marco ; Buzzaccarini, Giovanni ; Andrisani, Alessandra ; Laganà, Antonio Simone
engleski
The pharmacoeconomic impact of follitropin alpha biosimilars in IVF therapy in Europe: a report of the literature
Introduction: To study the impact of biosimilars in assisted reproductive treatments, we performed a review of the literature. Biosimilars are a bioequivalent chemical drug referred to the original. Their production is strongly requested in order to reduce drug cost and reduce health economic impact on national health system. In assisted reproductive treatments different gonadotropin biosimilars are being produced.Areas covered: For this reason, we performed a review of the literature on follitropin alfa Gonal-F biosimilar, Ovaleap and Bemfola, to assess their cost efficacy in national health system. Cost effective (CE) analysis and incremental cost- effectiveness ratio (ICER) were used as parameters for biosimilar impact evaluation in the national health system economy. In particular, they had only slight impact on cost reduction of recombinant follitropin alfa products in Europe.Expert opinion: considering cost-effective analysis, Gonal-F remains the first choice for national health systems. However, well- designed powered methods are strongly needed to assess biosimilars cost-effectiveness.
biosimilars ; ICER ; follitropin alpha ; health economy ; pharmacoeconomy.
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Podaci o izdanju
31
2021.
553-558
objavljeno
1473-7167
1744-8379
10.1080/14737167.2021.1910026
Povezanost rada
nije evidentirano