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Pregled bibliografske jedinice broj: 1138362

REPROGRAMMING OF TYROSINE PHOSPHORYLATION REGULATED SIGNALLING PATHWAYS BY HPV ONCOPROTEINS


ANITA SZALMÁS, VJEKOSLAV TOMAIĆ, PAOLA MASSIMI, ESZTER GYÖNGYÖSI , JÓZSEF KÓNYA1 , LAWRENCE BANKS
REPROGRAMMING OF TYROSINE PHOSPHORYLATION REGULATED SIGNALLING PATHWAYS BY HPV ONCOPROTEINS // (2017). Abstracts of the 5th Central European Forum for Microbiology, October 18-20, 2017, Keszthely, Hungary. Acta Microbiologica et Immunologica Hungarica, 64(Supplement 1), 105–192.
Keszthely, Hungary, 2017. str. 171-172 (pozvano predavanje, međunarodna recenzija, sažetak, ostalo)


CROSBI ID: 1138362 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
REPROGRAMMING OF TYROSINE PHOSPHORYLATION REGULATED SIGNALLING PATHWAYS BY HPV ONCOPROTEINS

Autori
ANITA SZALMÁS, VJEKOSLAV TOMAIĆ, PAOLA MASSIMI, ESZTER GYÖNGYÖSI , JÓZSEF KÓNYA1 , LAWRENCE BANKS

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, ostalo

Izvornik
(2017). Abstracts of the 5th Central European Forum for Microbiology, October 18-20, 2017, Keszthely, Hungary. Acta Microbiologica et Immunologica Hungarica, 64(Supplement 1), 105–192. / - , 2017, 171-172

Skup
5th Central European Forum for Microbiology

Mjesto i datum
Keszthely, Hungary, 18-20.10.2017

Vrsta sudjelovanja
Pozvano predavanje

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
HPV E7, PTPN14, PTPN21

Sažetak
Activation of signaling pathways ensuring cell growth are essential for the proliferative competence of human papillomavirus (HPV) infected cells. Kinases and phosphatases are the key regulators of cellular growth control pathways. Recently identified cellular targets of HPV E7 are certain cytoplasmic protein tyrosine kinases and phosphatases, such as Src, PTPN14, and PTPN21, which have been linked to the control of multiple cellular growth pathways. We showed that the E7 proteins of both high-risk and low-risk mucosal HPV types can interact with certain non-receptor kinases and phosphatases. These interactions can happen independently of pRb regulation. We also showed that E7 can influence the stability of these regulatory proteins, for example by inducing proteasome mediated degradation of certain cytoplasmic phosphatases.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)



POVEZANOST RADA


Projekti:
HRZZ-IP-2016-06-2246 - Rasvjetljivanje onkogenih funkcija E6/E7 HPV-a na različitim anatomskim mjestima (HPVHNC) (Tomaić, Vjekoslav, HRZZ - 2016-06) ( POIROT)

Ustanove:
Institut "Ruđer Bošković", Zagreb

Profili:

Avatar Url Vjekoslav Tomaić (autor)


Citiraj ovu publikaciju

ANITA SZALMÁS, VJEKOSLAV TOMAIĆ, PAOLA MASSIMI, ESZTER GYÖNGYÖSI , JÓZSEF KÓNYA1 , LAWRENCE BANKS
REPROGRAMMING OF TYROSINE PHOSPHORYLATION REGULATED SIGNALLING PATHWAYS BY HPV ONCOPROTEINS // (2017). Abstracts of the 5th Central European Forum for Microbiology, October 18-20, 2017, Keszthely, Hungary. Acta Microbiologica et Immunologica Hungarica, 64(Supplement 1), 105–192.
Keszthely, Hungary, 2017. str. 171-172 (pozvano predavanje, međunarodna recenzija, sažetak, ostalo)
ANITA SZALMÁS, VJEKOSLAV TOMAIĆ, PAOLA MASSIMI, ESZTER GYÖNGYÖSI , JÓZSEF KÓNYA1 , LAWRENCE BANKS (2017) REPROGRAMMING OF TYROSINE PHOSPHORYLATION REGULATED SIGNALLING PATHWAYS BY HPV ONCOPROTEINS. U: (2017). Abstracts of the 5th Central European Forum for Microbiology, October 18-20, 2017, Keszthely, Hungary. Acta Microbiologica et Immunologica Hungarica, 64(Supplement 1), 105–192..
@article{article, year = {2017}, pages = {171-172}, keywords = {HPV E7, PTPN14, PTPN21}, title = {REPROGRAMMING OF TYROSINE PHOSPHORYLATION REGULATED SIGNALLING PATHWAYS BY HPV ONCOPROTEINS}, keyword = {HPV E7, PTPN14, PTPN21}, publisherplace = {Keszthely, Hungary} }
@article{article, year = {2017}, pages = {171-172}, keywords = {HPV E7, PTPN14, PTPN21}, title = {REPROGRAMMING OF TYROSINE PHOSPHORYLATION REGULATED SIGNALLING PATHWAYS BY HPV ONCOPROTEINS}, keyword = {HPV E7, PTPN14, PTPN21}, publisherplace = {Keszthely, Hungary} }




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