engleski

Simultaneous occurrence of primary skin melanoma and its metastasis to the ampulla of vater : a case report

Malignant melanoma has a capability to disseminate widely to almost any organ in the body. The gastrointestinal tract is freguently involved by this tumor. Reports on metastatic melanoma of ampullary region and biliary system are rare. We describe a case of 46-year-old male patient who presented with obstructive jaundice. Pathohistologic analysis of endoscopic biopsy of the ampulla of Vater suggested metastatic melanoma. Two weeks before the patient underwent surgery due to an ulcerated tumor of the index-finger of the right hand. Pathohistological analysis showed acral melanoma (Clark V, Breslow V). Subsequently a Whipple resection of the pancreas, duodenum, and distal bile duct revealed a metastatic melanoma in the ampulla of Vater extending to the duodenal wall. The patient had brain metastasis 9 and 17 months after diagnosis, respectively, and died 20 months after initial presentation. The autopsy was not performed.

primary skin melanoma; metastatic melanoma; ampulla of Vater

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