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Pregled bibliografske jedinice broj: 1134442

Challenges in the diagnostics and treatment of ectopic ameloblastic carcinoma: a case report


Tarle, Marko; Müller, Danko; Tarle, Antonia; Blivajs, Igor; Aljinović Ratković, Naranđa; Knežević, Predrag
Challenges in the diagnostics and treatment of ectopic ameloblastic carcinoma: a case report // Croatian Medical Journal, 61 (2020), 3; 271-275 doi:10.3325/cmj.2020.61.271 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1134442 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Challenges in the diagnostics and treatment of ectopic ameloblastic carcinoma: a case report

Autori
Tarle, Marko ; Müller, Danko ; Tarle, Antonia ; Blivajs, Igor ; Aljinović Ratković, Naranđa ; Knežević, Predrag

Izvornik
Croatian Medical Journal (0353-9504) 61 (2020), 3; 271-275

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
ectopic ameloblastic carcinoma, skull base, odontogenic tumor, BRAF mutation

Sažetak
Ameloblastic carcinoma (AC) is a rare and aggressive malignant epithelial odontogenic tumor, most commonly located in the mandible or maxilla. An extremely rare extragnathic localization of AC with no connection to the jaws, ectopic ameloblastic carcinoma (EAC), has so far been described only three times. This report presents a 64-year-old male with skull base ameloblastic carcinoma and offers a review of diagnostic and treatment challenges related to EAC. Because of its rarity and histological similarity to other tumors, EAC is often misdiagnosed. This is why we established a pathohistological and immunohistochemical profile of EAC that differentiates it from histologically similar tumors. The most frequently used EAC treatment is radical surgical resection, but the majority of reviewed reports described local recurrence. Taking into consideration new scientific discoveries on the molecular pathogenesis of ameloblastoma, we are the first to have performed BRAF mutation analysis in an EAC patient. BRAF inhibitors offer promising results in the treatment of BRAF-positive ameloblastomas and should continue to be researched in AC and EAC patients. Finally, EAC should be considered in differential diagnosis of head and neck tumors outside the jaws

Izvorni jezik
Engleski



POVEZANOST RADA


Profili:

Avatar Url Marko Tarle (autor)

Avatar Url Predrag Knežević (autor)

Avatar Url Danko Müller (autor)

Citiraj ovu publikaciju

Tarle, Marko; Müller, Danko; Tarle, Antonia; Blivajs, Igor; Aljinović Ratković, Naranđa; Knežević, Predrag
Challenges in the diagnostics and treatment of ectopic ameloblastic carcinoma: a case report // Croatian Medical Journal, 61 (2020), 3; 271-275 doi:10.3325/cmj.2020.61.271 (međunarodna recenzija, članak, znanstveni)
Tarle, M., Müller, D., Tarle, A., Blivajs, I., Aljinović Ratković, N. & Knežević, P. (2020) Challenges in the diagnostics and treatment of ectopic ameloblastic carcinoma: a case report. Croatian Medical Journal, 61 (3), 271-275 doi:10.3325/cmj.2020.61.271.
@article{article, year = {2020}, pages = {271-275}, DOI = {10.3325/cmj.2020.61.271}, keywords = {ectopic ameloblastic carcinoma, skull base, odontogenic tumor, BRAF mutation}, journal = {Croatian Medical Journal}, doi = {10.3325/cmj.2020.61.271}, volume = {61}, number = {3}, issn = {0353-9504}, title = {Challenges in the diagnostics and treatment of ectopic ameloblastic carcinoma: a case report}, keyword = {ectopic ameloblastic carcinoma, skull base, odontogenic tumor, BRAF mutation} }
@article{article, year = {2020}, pages = {271-275}, DOI = {10.3325/cmj.2020.61.271}, keywords = {ectopic ameloblastic carcinoma, skull base, odontogenic tumor, BRAF mutation}, journal = {Croatian Medical Journal}, doi = {10.3325/cmj.2020.61.271}, volume = {61}, number = {3}, issn = {0353-9504}, title = {Challenges in the diagnostics and treatment of ectopic ameloblastic carcinoma: a case report}, keyword = {ectopic ameloblastic carcinoma, skull base, odontogenic tumor, BRAF mutation} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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