Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 1133716

ADP-ribosylation systems in bacteria and viruses


Mikolčević, Petra; Hloušek-Kasun, Andrea; Ahel, Ivan; Mikoč, Andreja
ADP-ribosylation systems in bacteria and viruses // Computational and Structural Biotechnology Journa, 19 (2021), 2366-2383 doi:10.1016/j.csbj.2021.04.023 (međunarodna recenzija, pregledni rad, znanstveni)


CROSBI ID: 1133716 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
ADP-ribosylation systems in bacteria and viruses

Autori
Mikolčević, Petra ; Hloušek-Kasun, Andrea ; Ahel, Ivan ; Mikoč, Andreja

Izvornik
Computational and Structural Biotechnology Journa (2001-0370) 19 (2021); 2366-2383

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, pregledni rad, znanstveni

Ključne riječi
ADP-ribosylation ; ADP-ribosyl transferase ; ADP-ribosyl hydrolase ; PARP ; PARG ; Macrodomain ; Toxin-antitoxin system

Sažetak
ADP-ribosylation is an ancient posttranslational modification present in all kingdoms of life. The system likely originated in bacteria where it functions in inter- and intra-species conflict, stress response and pathogenicity. It was repeatedly adopted via lateral transfer by eukaryotes, including humans, where it has a pivotal role in epigenetics, DNA-damage repair, apoptosis, and other crucial pathways including the immune response to pathogenic bacteria and viruses. In other words, the same ammunition used by pathogens is adapted by eukaryotes to fight back. While we know quite a lot about the eukaryotic system, expanding rather patchy knowledge on bacterial and viral ADP-ribosylation would give us not only a better understanding of the system as a whole but a fighting advantage in this constant arms race. By writing this review we hope to put into focus the available information and give a perspective on how this system works and can be exploited in the search for therapeutic targets in the future. The relevance of the subject is especially highlighted by the current situation of being amid the world pandemic caused by a virus harbouring and dependent on a representative of such a system.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Biotehnologija, Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)

Napomena
Petra Mikolčević and Andrea Hloušek-Kasun contributed equally to this work



POVEZANOST RADA


Projekti:
HRZZ-IP-2016-06-4242 - Istraživanje uloge proteinske modifikacije ADP-ribozilacije kod bakterija (ADPRIBAC) (Mikoč, Andreja, HRZZ - 2016-06) ( POIROT)
HRZZ-IP-CORONA-IP-CORONA-2020-04-2041 - Inhibitori koronavirusnih makrodomena – novi pristup liječenju bolesti uzrokovane koronavirusima (Mikoč, Andreja, HRZZ - 2020-04) ( POIROT)
EK-H2020-867468 - Unlocking the antibiotic production potential in soil bacteria Streptomyces coelicolor (STREPUNLOCKED) (Mikoč, Andreja; Mikolčević, Petra, EK - H2020-WF-01-2018) ( POIROT)

Ustanove:
Institut "Ruđer Bošković", Zagreb

Citiraj ovu publikaciju

Mikolčević, Petra; Hloušek-Kasun, Andrea; Ahel, Ivan; Mikoč, Andreja
ADP-ribosylation systems in bacteria and viruses // Computational and Structural Biotechnology Journa, 19 (2021), 2366-2383 doi:10.1016/j.csbj.2021.04.023 (međunarodna recenzija, pregledni rad, znanstveni)
Mikolčević, P., Hloušek-Kasun, A., Ahel, I. & Mikoč, A. (2021) ADP-ribosylation systems in bacteria and viruses. Computational and Structural Biotechnology Journa, 19, 2366-2383 doi:10.1016/j.csbj.2021.04.023.
@article{article, year = {2021}, pages = {2366-2383}, DOI = {10.1016/j.csbj.2021.04.023}, keywords = {ADP-ribosylation, ADP-ribosyl transferase, ADP-ribosyl hydrolase, PARP, PARG, Macrodomain, Toxin-antitoxin system}, journal = {Computational and Structural Biotechnology Journa}, doi = {10.1016/j.csbj.2021.04.023}, volume = {19}, issn = {2001-0370}, title = {ADP-ribosylation systems in bacteria and viruses}, keyword = {ADP-ribosylation, ADP-ribosyl transferase, ADP-ribosyl hydrolase, PARP, PARG, Macrodomain, Toxin-antitoxin system} }
@article{article, year = {2021}, pages = {2366-2383}, DOI = {10.1016/j.csbj.2021.04.023}, keywords = {ADP-ribosylation, ADP-ribosyl transferase, ADP-ribosyl hydrolase, PARP, PARG, Macrodomain, Toxin-antitoxin system}, journal = {Computational and Structural Biotechnology Journa}, doi = {10.1016/j.csbj.2021.04.023}, volume = {19}, issn = {2001-0370}, title = {ADP-ribosylation systems in bacteria and viruses}, keyword = {ADP-ribosylation, ADP-ribosyl transferase, ADP-ribosyl hydrolase, PARP, PARG, Macrodomain, Toxin-antitoxin system} }

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


Citati





    Contrast
    Increase Font
    Decrease Font
    Dyslexic Font