Association of interleukin-10 G microsatellite polymorphism with the susceptibility of ankylosing spondylitis (CROSBI ID 295944)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Mastrovic Radoncic, Ksenija ; Kaluza-Schilling, Wiebke ; Cikes, Nada ; Marker-Hermann, Elisabeth
engleski
Association of interleukin-10 G microsatellite polymorphism with the susceptibility of ankylosing spondylitis
Study suggests an association of IL10.G poly- morphisms with AS which might contribute to the increased or decreased susceptibility to AS. IL10.G8 and G7 microsatellites alleles appear as protective alleles against the development of AS in the German subjects investigated here. Allele IL10.G9 seems to be a risk factor for the development of AS. This protective effect of variant promoter alleles could be related to differences in IL- 10 production, which may be clinically relevant.
IL10 microsatellite, polymorphisms, ankylosing spondylitis
nije evidentirano
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Podaci o izdanju
Povezanost rada
Kliničke medicinske znanosti, Temeljne medicinske znanosti