engleski

Prevention of necrotic enteritis in piglets by vaccination of pregnant gilts with a Clostridium perfringens type C and D bacterin-toxoid

On a large pig farm with a known history of necrotic enteritis 12 pregnant gilts were vaccinated s.c. 7 and 2 weeks before expected farrowing with a commercial bacterin-toxoid preparation of a toxogenic strains C. perfringens type C and D (Dizevak-Pliva, Zagreb). At the farrowing the titers of beta-antitoxins in serum samples from vaccinated gilts ranged from 9.0 to 26.0 IU/mL with a mean value of 14.16 IU/mL. Colostral titers varied from 12.0 IU/mL with a mean of 16.12 IU/mL. On the second day of life the mean serum titres between litters differed greatly from 4.75 to 24.0 IU/mL. By the age of 7 days the average serum titers were commonly lower and varied between the litters from 2.25 to 15.0 IU/ml, with a low of 1.5 to a high of 16.0 IU/ml in single animals. Ten (8.47 percentage) out of a total of 118 piglets from vaccinated gilts died during the first 7 days of life but the losses were not caused by C. perfringens infection. In unvaccinated control animals 18 (15.9 percent) of 113 piglets died, eleven of them with clinical and pathoanatomical signs of necrotic enteritis. The affected piglets predominantly succumbed in the first 4 days of life. These data indicate that the investigated bacterin-toxoid can succesfully used in immunoprophylaxis of necrotic enteritis in piglets.

clostridium perfringens type C and D ; prevention of necrotic enteritis in piglets ; gilt vaccination

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