Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 1132367

Seroprevalence of SARS-CoV-2 infection among children in Children’s Hospital Zagreb during the initial and second wave of COVID-19 pandemic in Croatia


Leniček Krleža, Jasna; Zrinski Topić, Renata; Stevanović, Vladimir; Lukić-Grlić, Amarela; Tabain, Irena; Mišak, Zrinjka; Roić, Goran; Kaić, Bernard; Mayer, Dijana; Hruškar, Željka et al.
Seroprevalence of SARS-CoV-2 infection among children in Children’s Hospital Zagreb during the initial and second wave of COVID-19 pandemic in Croatia // Biochemia medica, 31 (2021), 2; 283-294 doi:10.11613/BM.2021.020706 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1132367 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Seroprevalence of SARS-CoV-2 infection among children in Children’s Hospital Zagreb during the initial and second wave of COVID-19 pandemic in Croatia

Autori
Leniček Krleža, Jasna ; Zrinski Topić, Renata ; Stevanović, Vladimir ; Lukić-Grlić, Amarela ; Tabain, Irena ; Mišak, Zrinjka ; Roić, Goran ; Kaić, Bernard ; Mayer, Dijana ; Hruškar, Željka ; Barbić, Ljubo ; Vilibić-Čavlek, Tatjana

Izvornik
Biochemia medica (1330-0962) 31 (2021), 2; 283-294

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
COVID-19 ; SARS-CoV-2 ; anti-SARS-CoV-2 antibodies ; children ; seroprevalence

Sažetak
Introduction: The study aimed to investigate the prevalence and titres of anti-SARS-CoV-2 antibodies in children treated at the Children’s Hospital Zagreb in the first and the second wave of the COVID-19 pandemic. Statistical significance of difference at two time points was done to determine how restrictive epidemiological measures and exposure of children to COVID-19 infection affect this prevalence in different age groups.Materials and methods: At the first time point (13th to 29th May 2020), 240 samples and in second time point (24th October to 23rd November 2020), 308 serum samples were tested for anti- SARS-CoV-2 antibodies by enzyme-linked immunosorbent assay (ELISA) and electrochemilumines-cence immunoassay (ECLIA). Confirmation of results and titre determination was done using virus micro-neutralization test. Subjects were divided according to gender, age and epidemiological history. Results: Seroprevalence of anti-SARS-CoV-2 antibodies differs significantly in two time points (P = 0.010). In first time point 2.9% of seropositive children were determined and in second time point 8.4%. Statistically significant difference (P = 0.007) of seroprevalence between two time points was found only in a group of children aged 11-19 years. At the first time point, all seropositive children were asymptomatic with titre < 8. At the second time point, 69.2% seropositive children were asymptomatic with titre ≥ 8. Conclusions: The prevalence of anti-SARS-CoV-2 antibodies was significantly lower at the first time point than at the second time point. Values of virus micro- neutralization test showed that low titre in asymptomatic children was not protective at the first time point but in second time point all seropositive children had protective titre of anti-SARS-CoV-2 antibodies.

Izvorni jezik
Engleski

Znanstvena područja
Javno zdravstvo i zdravstvena zaštita



POVEZANOST RADA


Ustanove:
Hrvatski zavod za javno zdravstvo,
Veterinarski fakultet, Zagreb,
Medicinski fakultet, Zagreb,
Klinika za dječje bolesti

Citiraj ovu publikaciju

Leniček Krleža, Jasna; Zrinski Topić, Renata; Stevanović, Vladimir; Lukić-Grlić, Amarela; Tabain, Irena; Mišak, Zrinjka; Roić, Goran; Kaić, Bernard; Mayer, Dijana; Hruškar, Željka et al.
Seroprevalence of SARS-CoV-2 infection among children in Children’s Hospital Zagreb during the initial and second wave of COVID-19 pandemic in Croatia // Biochemia medica, 31 (2021), 2; 283-294 doi:10.11613/BM.2021.020706 (međunarodna recenzija, članak, znanstveni)
Leniček Krleža, J., Zrinski Topić, R., Stevanović, V., Lukić-Grlić, A., Tabain, I., Mišak, Z., Roić, G., Kaić, B., Mayer, D. & Hruškar, Ž. (2021) Seroprevalence of SARS-CoV-2 infection among children in Children’s Hospital Zagreb during the initial and second wave of COVID-19 pandemic in Croatia. Biochemia medica, 31 (2), 283-294 doi:10.11613/BM.2021.020706.
@article{article, year = {2021}, pages = {283-294}, DOI = {10.11613/BM.2021.020706}, keywords = {COVID-19, SARS-CoV-2, anti-SARS-CoV-2 antibodies, children, seroprevalence}, journal = {Biochemia medica}, doi = {10.11613/BM.2021.020706}, volume = {31}, number = {2}, issn = {1330-0962}, title = {Seroprevalence of SARS-CoV-2 infection among children in Children’s Hospital Zagreb during the initial and second wave of COVID-19 pandemic in Croatia}, keyword = {COVID-19, SARS-CoV-2, anti-SARS-CoV-2 antibodies, children, seroprevalence} }
@article{article, year = {2021}, pages = {283-294}, DOI = {10.11613/BM.2021.020706}, keywords = {COVID-19, SARS-CoV-2, anti-SARS-CoV-2 antibodies, children, seroprevalence}, journal = {Biochemia medica}, doi = {10.11613/BM.2021.020706}, volume = {31}, number = {2}, issn = {1330-0962}, title = {Seroprevalence of SARS-CoV-2 infection among children in Children’s Hospital Zagreb during the initial and second wave of COVID-19 pandemic in Croatia}, keyword = {COVID-19, SARS-CoV-2, anti-SARS-CoV-2 antibodies, children, seroprevalence} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Citati





    Contrast
    Increase Font
    Decrease Font
    Dyslexic Font