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Pregled bibliografske jedinice broj: 1130873

Brain MRI post-processing with MAP07 in the preoperative evaluation of patients with pharmacoresistant epilepsy - Croatian single centre experience


Bujan Kovac, Andreja; Petelin Gadze, Zeljka; Rados, Milan; Krbot Skoric, Magdalena; Mrak, Goran; Nemir, Jakob; Milosevic, Milan; Hajnsek, Sanja
Brain MRI post-processing with MAP07 in the preoperative evaluation of patients with pharmacoresistant epilepsy - Croatian single centre experience // Clinical Neurology and Neurosurgery, 201 (2021), 106426-7 doi:10.1016/j.clineuro.2020.106426 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1130873 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Brain MRI post-processing with MAP07 in the preoperative evaluation of patients with pharmacoresistant epilepsy - Croatian single centre experience
(Brain MRI post-processing with MAP07 in the preoperative evaluation of patients with pharmacoresistant epilepsy – Croatian single centre experience)

Autori
Bujan Kovac, Andreja ; Petelin Gadze, Zeljka ; Rados, Milan ; Krbot Skoric, Magdalena ; Mrak, Goran ; Nemir, Jakob ; Milosevic, Milan ; Hajnsek, Sanja

Izvornik
Clinical Neurology and Neurosurgery (0303-8467) 201 (2021); 106426-7

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Brain MRI postprocessing ; Epilepsy ; Hippocampal sclerosis ; Malformation of cortical development

Sažetak
Objective: This study aimed to determine the role of brain MRI post-processing method MAP07 (Morphometric Analysis Program) in detecting epileptogenic brain lesions in patients with pharmacoresistant epilepsy (PE). MAP07 is a sophisticated diagnostic program that offers several morphometric maps and facilitates the detection and localization of hippocampal sclerosis (HS), focal cortical dysplasias (FCD), and other types of cortical malformations, which could be undetected by conventional visual MRI analysis (CVA). Methods: 120 patients aged > 16 years with PE have been recruited. 3 T MRI was performed according to epilepsy imaging protocol followed by image postprocessing with a fully automated MATLAB script, MAP07, by applying SPM5 algorithms. Statistical analysis was performed in IBM SPSS Statistics, version 25.0. Results: Analysis in our patients showed a high sensitivity of MAP07 with low specificity and with a high proportion of false-positive patients. After MRI analysis, out of 120 patients, 32 were found to have no structural abnormalities by conventional visual analysis in whom after MAP07 in 5 patients structural lesions were found (in one HS, in one FCD, in two perinatal vascular lesions, and in one hippocampal hyperintensity). There was a quite high overall coincidence of the findings of MAP07 and MRI for the detection of FCD, HS, perinatal ischemia/chronic vascular lesions, heterotopias, and polymicrogyria (kappa coefficient above 0.700). Conclusions: MAP07 analysis is a useful, additional, and automated method that may guide re-evaluation of MRI by highlighting suspicious cortical regions, as a complementary method to CVA, by enhancing the visualization of cortical malformations and lesions.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti, Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)



POVEZANOST RADA


Ustanove:
Fakultet elektrotehnike i računarstva, Zagreb,
Medicinski fakultet, Zagreb,
Klinički bolnički centar Zagreb

Poveznice na cjeloviti tekst rada:

doi

Citiraj ovu publikaciju:

Bujan Kovac, Andreja; Petelin Gadze, Zeljka; Rados, Milan; Krbot Skoric, Magdalena; Mrak, Goran; Nemir, Jakob; Milosevic, Milan; Hajnsek, Sanja
Brain MRI post-processing with MAP07 in the preoperative evaluation of patients with pharmacoresistant epilepsy - Croatian single centre experience // Clinical Neurology and Neurosurgery, 201 (2021), 106426-7 doi:10.1016/j.clineuro.2020.106426 (međunarodna recenzija, članak, znanstveni)
Bujan Kovac, A., Petelin Gadze, Z., Rados, M., Krbot Skoric, M., Mrak, G., Nemir, J., Milosevic, M. & Hajnsek, S. (2021) Brain MRI post-processing with MAP07 in the preoperative evaluation of patients with pharmacoresistant epilepsy - Croatian single centre experience. Clinical Neurology and Neurosurgery, 201, 106426-7 doi:10.1016/j.clineuro.2020.106426.
@article{article, author = {Bujan Kovac, Andreja and Petelin Gadze, Zeljka and Rados, Milan and Krbot Skoric, Magdalena and Mrak, Goran and Nemir, Jakob and Milosevic, Milan and Hajnsek, Sanja}, year = {2021}, pages = {106426-7}, DOI = {10.1016/j.clineuro.2020.106426}, keywords = {Brain MRI postprocessing, Epilepsy, Hippocampal sclerosis, Malformation of cortical development}, journal = {Clinical Neurology and Neurosurgery}, doi = {10.1016/j.clineuro.2020.106426}, volume = {201}, issn = {0303-8467}, title = {Brain MRI post-processing with MAP07 in the preoperative evaluation of patients with pharmacoresistant epilepsy - Croatian single centre experience}, keyword = {Brain MRI postprocessing, Epilepsy, Hippocampal sclerosis, Malformation of cortical development} }
@article{article, author = {Bujan Kovac, Andreja and Petelin Gadze, Zeljka and Rados, Milan and Krbot Skoric, Magdalena and Mrak, Goran and Nemir, Jakob and Milosevic, Milan and Hajnsek, Sanja}, year = {2021}, pages = {106426-7}, DOI = {10.1016/j.clineuro.2020.106426}, keywords = {Brain MRI postprocessing, Epilepsy, Hippocampal sclerosis, Malformation of cortical development}, journal = {Clinical Neurology and Neurosurgery}, doi = {10.1016/j.clineuro.2020.106426}, volume = {201}, issn = {0303-8467}, title = {Brain MRI post-processing with MAP07 in the preoperative evaluation of patients with pharmacoresistant epilepsy – Croatian single centre experience}, keyword = {Brain MRI postprocessing, Epilepsy, Hippocampal sclerosis, Malformation of cortical development} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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