hrvatski

Kronična bubrežna bolest i arterijska hipertenzija

: Chronic kidney disease (CKD) represents a disease in which the kidney is damaged or has had gradual losses in kidney function for a minimum period of 3 months. CKD is manifested with the growth of urea and creatinin concentration, dysregulation in sodium, calcium, or phosphate concentration in blood. CKD is strongly associated with arterial hypertension, which can either be a cause or effect of CKD. Management of arterial hypertension is crucial for patients with CKD as it leads to a slower progression of the disease. Pathophysiology of CKD associated with arterial hypertension is multifactorial with different mechanisms which participate in arterial hypertension. The mechanisms that are responsible for arterial hypertension in CKD include sodium dysregulation, enhance sympathetic activity, and alterations in the renin-angiotensin system. Antihypertensive treatment in CKD and arterial hypertension is crucial and involves a correct choice of diuretics based on estimated glomerular filtration rate (GFR). There are various methods to prevent CKD and arterial hypertension, the most important ones being low sodium intake, increased physical activity, stress management, and quitting smoking.

kronična bubrežna bolest ; arterijska hipertenzija ; renin angiotenzinski sustav ; antihipertenzivi

nije evidentirano

engleski

Chronic kidney disease and arterial hypertension

: Chronic kidney disease (CKD) represents a disease in which the kidney is damaged or has had gradual losses in kidney function for a minimum period of 3 months. CKD is manifested with the growth of urea and creatinin concentration, dysregulation in sodium, calcium, or phosphate concentration in blood. CKD is strongly associated with arterial hypertension, which can either be a cause or effect of CKD. Management of arterial hypertension is crucial for patients with CKD as it leads to a slower progression of the disease. Pathophysiology of CKD associated with arterial hypertension is multifactorial with different mechanisms which participate in arterial hypertension. The mechanisms that are responsible for arterial hypertension in CKD include sodium dysregulation, enhance sympathetic activity, and alterations in the renin-angiotensin system. Antihypertensive treatment in CKD and arterial hypertension is crucial and involves a correct choice of diuretics based on estimated glomerular filtration rate (GFR). There are various methods to prevent CKD and arterial hypertension, the most important ones being low sodium intake, increased physical activity, stress management, and quitting smoking.

chronic kidney disease ; arterial hypertension ; renin angiotensin system ; antihypertensives

nije evidentirano