engleski

Sleep disorders and lower urinary tract symptoms in obese patients

Introduction/Objectives: Sleep disorders (according to ICSD-3, International Classification of Sleep Disorders, 3rd ed. ; in DSM-5, Diagnostic and Statistical Manual of Mental Disorders – 5th ed. Sleep-Wake Disorders) are common nowadays problem. They are caused by many reasons (psychiatric, neurologic, environmental, endocrine etc.). Also, there is various spectrum of symptoms and signs what we understand under the term sleep disorders and classifications vary. Most common entities are: insomnia, hypersomnolence, sleep apnea, narcolepsy etc. Lower urinary tract symptoms (LUTS) are disturbing and can be connected to sleep disorders. We wanted to assess connection between sleep disorders and lower urinary tract symptoms in obese patients in Croatia. Participants, Materials/Methods: This was a prospective study carried out in tertiary healthcare centre. 111 participants (81 women (72.97%), 30 men (27.03%)), mean age 49.03 ± 12.21 years, BMI>30 were included. Following questionnaires, were used to assess LUTS: ICIQ- OAB and ICIQ-OABqol (both currently under validation for Croatian language). Sleep disorders were evaluated through general information questionnaire where patients needed to mark all illnesses (out of 14) they have problem with. Pearson’s correlation coefficient was used. Results: Our study found significant correlation in the overall result on the overreactive bladder questionnaire (ICIQ-OAB) and sleep disorders: r=0.34 (p=0.001). Also, increased urinary frequency and sleep disorders are significantly connected: r=0.21 (p=0.03). Nocturia and sleep disorders significantly correlate as r=0.34 (p=0.001). Sleep disorders are significantly related to urinary urgency r=0.3 (p=0.001). Moreover, significant correlation is found between urinary incontinence and sleep disorders: r=0.23 (p=0.02). Significant correlation is found between the overall results of the impact of urinary symptoms on the quality of life questionnaire (ICIQ-OABqol) with sleep disorders: r=0.25 (p=0.01). On the last question on the impact of urinary symptoms on the quality of life questionnaire – ICIQ-OABqol (where patients need to assess overall impact of urinary symptoms on everyday life choosing a number between 0 (not at all) and 10 (a great deal)) is significantly correlated to sleep disorders: r=0.24 (p=0.01). Conclusion: This study has shown significant preliminary results in addition to indicating a correlation between sleep disorders and LUTS in Croatian obese patients. In the future, our study will consider a possible causal connection using the Pittsburgh Sleep Quality Index, Insomnia Severity Index and Epworth Sleepiness Scale.

sleep disorders ; LUTS ; obesity

nije evidentirano