Assessment of microvascular reactivity in randomly selected adult population EHUH study Croatian scientific foundation (CROSBI ID 702798)
Prilog sa skupa u časopisu | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Jukić, Ivana ; Stupin, Ana ; Kolar, Luka ; Perić, Leon ; Vincetić, Ivo ; Šušnjara, Petar ; Jelaković, Ana ; Dika, Živka ; Karanović, Sandra ; Matašin, Marija ; Krtalić, Branimir ; Jelaković, Bojan ; Drenjančević, Ines
engleski
Assessment of microvascular reactivity in randomly selected adult population EHUH study Croatian scientific foundation
Objective. To assess the forearm skin microvascular reactivity and anthropometric parameters in randomly selected population and seek the differences between a group of people who had elevated blood pressure at the time of measurement and those who were normotensive. Design and method. Total of 148 randomly selected individuals (50 men/98 women) participated in this study. The exclusion criteria were less than 1l of urine collected at 24h, and creatinine values below the reference values. Forthy eight individuals included in this study had arterial hypertension (HT) and 44 had normal arterial blood pressure values (NT). Post-occlusive reactive hyperemia (PORH) in skin microcirculation following 1 minute of vascular occlusion period was assessed using laser Doppler flowmetry. Anthropometric parameters, blood pressure, heart rate were measured, and 24-hour urine was collected to sodium excretion and creatinine measurement. P< 0, 05 was considered statistically significant. Results. Sistolic (SBP), diastolic (DBP) and mean (MAP) arterial blood pressure were significantly higher, while PORH was significantly lower in HT group compared to NT individuals. HT had higher body mass index (BMI) and waist circumference, while there were no differences in heart rate between HT and NT group. In HT individuals, PORH was negatively associated with waist circumference (r=-0, 438), and positively associated with heart rate (r=0, 316). Sodium excretion was positively associated with DBP (r=0, 361). In NT group, PORH was negatively associated with SBP (r=-0, 362) and MAP (r=-0, 37). SBP and MAP were positively associated with BMI (r=0, 484, r=0, 312) and waist circumference (r=0, 421, r=0, 319). Sodium excretion was positively associated with BMI (r=0, 546) and waist circumference (r=0, 523). Analyzes of all individuals together showed that PORH was negatively associated with BMI (r=-0, 253), SBP (r=-0, 274) and MAP (r=-0, 24), while BMI was positively associated with SBP (r=0, 359), DBP (r=0, 219) and MAP (r=0, 312). Conclusions. High blood pressure attenuated microvascular function. Arterial blood pressure is related to obesity (BMI, waist circumference).
skin microvascular reactivity ; laser Doppler flowmetry ; anthropometric parameters ; blood pressure
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Podaci o prilogu
e328-e328.
2021.
nije evidentirano
objavljeno
Podaci o matičnoj publikaciji
Journal of hypertension
0263-6352
1473-5598
Podaci o skupu
Meeting of the European Society of Hypertension (ESH) and International Society of Hypertension (ESH-ISH 2021)
poster
11.04.2021-14.04.2021
online
Povezanost rada
Kliničke medicinske znanosti, Temeljne medicinske znanosti