engleski

New-onset diabetes after kidney transplantation: diagnosis, risk factors, and management

New-onset diabetes after transplantation (NODAT) is a frequent and severe complication after renal transplantation. Risk factors for NODAT are non- modifiable (non-white ethnicity, older age, genetic predisposition, previous glucose intolerance, steroid therapy, male donor, and others) and modifiable (obesity, viral infections, and immunosuppressive therapy). Glucose control is needed immediately after renal transplantation and after 3, 6, and 12 months and annual glucose control is needed after that period. Pharmacotherapy includes oral hypoglycemic agents (in most cases metformin, sulfonylureas, and dipeptidyl peptidase-4 (DPP-4) inhibitors) and insulin (in most cases biphasic insulin several times daily or intensive insulin therapy). Regular annual screening should be performed for micro- and macrovascular complications of diabetes.

new-onset diabetes after transplantation (NODAT) ; immunosuppressive drugs ; diabetes management ; kidney

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