engleski

Anti-Inflammatory Potential of Quatro Eggs Consumption in Healthy Young Individuals

Introduction: Our previous study demonstrated mild increase in serum concentration of anti- inflammatory cytokine IL-10 after comsuption of omega-3 polyunsaturated fatty acids enriched hen eggs in young healthy participants (Stupin et al., 2020). Therefore, the aim of this study was to determine serum concentrations of inflammatory and anti-inflammatory cytokines in young healthy individuals who consumed hen eggs enriched with four components - omega-3 polyunsaturated fatty acids, vitamin E, lutein and selenium. Methods: Randomized, double-blind placebo- controlled study was conducted in healthy young subjects (N=35) who consumed 3 chicken eggs per day for 3 weeks. Subjects in the "Quatro" group consumed enriched hen eggs, and control subjects consumed ordinary hen eggs, produced on the same farm. Serum concentration of IL- 17A, IL-10, IL-6 and TNF-alpha was determined by commercially available kit and analyzed on Luminex platform. One way ANOVA was conducted for statistical analysis with Tukey post hoc test ; p<0.05 was considered statistically significant. Results: Three-weeks dietary intake of eggs did not cause a significant change in any of cytokines’ concentration in control or experimental group or between groups. Discussion: Coordination of different immune cells and regulation of their activity is crucial for establishing an effective immune defense. This task is often accomplished by secreting cytokines and chemokines. Consumption of Quatro eggs did not affect serum levels of cytokines. probably due to the lack of stimulation of the immune system in healthy individuals (i.e. no presence of any disease that engage immune responses). Conclusion: Present results suggest that consumption of Quatro or regular eggs does not influence cytokine levels in serum in healthy young individuals.

cytokines, eggs, IL-17A, IL-10, IL-6, TNF-alpha

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