hrvatski

A dose-dependent relationship between quetiapine and QTc interval

Quetiapine is a second-generation antipsychotic and one of its seri- ous side effects is QTc prolongation, which is related to increased risk of developing life-threatening arrhythmias, particularly torsades de pointes.he following case suggests a possible relationship between QTc in- terval and the quetiapine dose as a result of successive measurements of the length of QTc intervals during the gradual reduction of the quetiapine dose (and escitalopram) in a patient with prolonged QTc interval. Our observation indicates that the link between the length of the QTc interval and quetiapine dose exists, even within the recommended therapeutic dose range.

quetiapine dose ; QTc ; case report

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