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Pregled bibliografske jedinice broj: 1117819

Diverse SARS-CoV-2 variants preceded the initial COVID-19 outbreak in Croatia


Rokić, Filip; Trgovec-Greif, Lovro; Sučić, Neven; Čemeljić, Noa; Grbeša Cekinović, Đurđica; Svedružić, Željko; Rukavina, Tomislav; Vugrek, Oliver; Jurak, Igor
Diverse SARS-CoV-2 variants preceded the initial COVID-19 outbreak in Croatia // Archives of virology (2021) doi:10.1007/s00705-021-05029-7 (znanstveni, prihvaćen)


CROSBI ID: 1117819 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Diverse SARS-CoV-2 variants preceded the initial COVID-19 outbreak in Croatia

Autori
Rokić, Filip ; Trgovec-Greif, Lovro ; Sučić, Neven ; Čemeljić, Noa ; Grbeša Cekinović, Đurđica ; Svedružić, Željko ; Rukavina, Tomislav ; Vugrek, Oliver ; Jurak, Igor

Vrsta, podvrsta
Radovi u časopisima, znanstveni

Izvornik
Archives of virology (2021)

Status rada
Prihvaćen

Ključne riječi
SARS-CoV-2 ; Croatia

Sažetak
We developed a next-generation SARS-CoV-2 sequencing platform and obtained the first SARS- CoV-2 sequences from patients in Croatia at the beginning of the COVID-19 outbreak in the spring of 2020. Integrating the sequencing and the epidemiological data, we show that patients were infected with different SARS-CoV-2 variants belonging to different clades (mostly G and GH). This result confirms that there was widespread virus transmission early in 2020. Interestingly, we identified a unique mutation resulting in a V13I substitution in Nsp5A, the main viral protease, in a patient who had not received antiviral therapy.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Interdisciplinarne prirodne znanosti, Javno zdravstvo i zdravstvena zaštita, Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)



POVEZANOST RADA


Ustanove:
Hrvatski zavod za javno zdravstvo,
Medicinski fakultet, Rijeka,
Institut "Ruđer Bošković", Zagreb,
Sveučilište u Rijeci - Odjel za biotehnologiju

Citiraj ovu publikaciju

Rokić, Filip; Trgovec-Greif, Lovro; Sučić, Neven; Čemeljić, Noa; Grbeša Cekinović, Đurđica; Svedružić, Željko; Rukavina, Tomislav; Vugrek, Oliver; Jurak, Igor
Diverse SARS-CoV-2 variants preceded the initial COVID-19 outbreak in Croatia // Archives of virology (2021) doi:10.1007/s00705-021-05029-7 (znanstveni, prihvaćen)
Rokić, F., Trgovec-Greif, L., Sučić, N., Čemeljić, N., Grbeša Cekinović, Đ., Svedružić, Ž., Rukavina, T., Vugrek, O. & Jurak, I. (2021) Diverse SARS-CoV-2 variants preceded the initial COVID-19 outbreak in Croatia. Prihvaćen za objavljivanje u Archives of virology. [Preprint] doi:10.1007/s00705-021-05029-7.
@unknown{unknown, year = {2021}, DOI = {10.1007/s00705-021-05029-7}, keywords = {SARS-CoV-2, Croatia}, journal = {Archives of virology}, doi = {10.1007/s00705-021-05029-7}, title = {Diverse SARS-CoV-2 variants preceded the initial COVID-19 outbreak in Croatia}, keyword = {SARS-CoV-2, Croatia} }
@unknown{unknown, year = {2021}, DOI = {10.1007/s00705-021-05029-7}, keywords = {SARS-CoV-2, Croatia}, journal = {Archives of virology}, doi = {10.1007/s00705-021-05029-7}, title = {Diverse SARS-CoV-2 variants preceded the initial COVID-19 outbreak in Croatia}, keyword = {SARS-CoV-2, Croatia} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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