Evidence-Based Management of Chronic Urticaria in Children (CROSBI ID 292396)
Prilog u časopisu | stručni rad | međunarodna recenzija
Podaci o odgovornosti
Pavić, Ivan ; Hojsak, Iva ; Čepin-Bogović, Jasna
engleski
Evidence-Based Management of Chronic Urticaria in Children
Chronic urticaria (CU) in children is a distressful disorder that can often be challenging to treat. Elimination or treatment of eliciting stimulus is the first step in the management of CU ; however, in the majority of cases, the cause remains unknown. According to currently available guidelines, H1- antihistamines are still first-line therapy for CU in children. Unfortunately, regularly approved doses relieve symptoms in <50% of patients, necessitating an up to 4-fold dose increase. However, in some patients, even high doses of H1-antihistamines fail to produce satisfactory results, leaving place for new therapeutic strategies in the treatment of CU ; first to add either leukotriene antagonist or H2-antihistamine. In severe, unresponsive cases, other therapeutic approaches should be considered. However, it is important to be familiar with the possible side effects, because some of these approaches imply off- label use of drugs. This review presents a summary of the evidence on the treatment of CU in pediatric patients available up to January 2012.
chronic urticaria ; children
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Podaci o izdanju
25 (4)
2012.
198-207
objavljeno
2151-321X
10.1089/ped.2012.0149