Dental management in osteogenesis imperfecta (CROSBI ID 292030)
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Podaci o odgovornosti
Brkić, Hrvoje ; Savić Pavičin, Ivana
engleski
Dental management in osteogenesis imperfecta
Osteogenesis imperfecta is a very rare heterogeneous genetic disorder associated with the development of connective tissue resulting in fragile bones and frequent fractures. More than 50% of patients affected with osteogenesis imperfecta have a hereditary develop- mental disorder known as dentinogenesis imperfecta. Dentinogenesis imperfecta is caused by irregularities in the formation, composition and organization of dentin matrix during tooth development. It is caused by mutations of the genes that encode basic proteins of the organic matrix, collagens and phosphoproteins. The purpose of this review is to describe the histopathologic and clinical features of teeth typical of dentinogenesis imperfecta type I, which occurs within osteogenesis imperfecta, with special emphasis on targeted dental treatment to achieve optimal rehabilitation of the masticatory system.
developmental bone disease ; dentinogenesis imperfecta ; rehabilitation
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