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Pregled bibliografske jedinice broj: 1113445

Comprehensive Review of Knee Osteoarthritis Pharmacological Treatment and the Latest Professional Societies’ Guidelines


Primorac, Damir; Molnar, Vilim; Matišić, Vid; Hudetz, Damir; Jeleč, Željko; Rod, Eduard; Čukelj, Fabijan; Vidović, Dinko; Vrdoljak, Trpimir; Dobričić, Borut et al.
Comprehensive Review of Knee Osteoarthritis Pharmacological Treatment and the Latest Professional Societies’ Guidelines // Pharmaceuticals, 14 (2021), 3; 205, 20 doi:10.3390 (međunarodna recenzija, članak, znanstveni)


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Naslov
Comprehensive Review of Knee Osteoarthritis Pharmacological Treatment and the Latest Professional Societies’ Guidelines

Autori
Primorac, Damir ; Molnar, Vilim ; Matišić, Vid ; Hudetz, Damir ; Jeleč, Željko ; Rod, Eduard ; Čukelj, Fabijan ; Vidović, Dinko ; Vrdoljak, Trpimir ; Dobričić, Borut ; Antičević, Darko ; Smolić, Martina ; Miškulin, Mladen ; Ćaćić, Damir ; Borić, Igor

Izvornik
Pharmaceuticals (1424-8247) 14 (2021), 3; 205, 20

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
knee osteoarthritis ; guidelines ; drug therapy ; pharmacogenomics ; intra-articular injections ; mesenchymal stem cells

Sažetak
Osteoarthritis is the most common musculoskeletal progressive disease, with the knee as the most commonly affected joint in the human body. While several new medications are still under research, many symptomatic therapy options, such as analgesics (opioid and non-opioid), nonsteroid anti-inflammatory drugs, symptomatic slow- acting drugs in osteoarthritis, and preparations for topical administration, are being used, with a diverse clinical response and inconsistent conclusions across various professional societies guidelines. The concept of pharmacogenomic- guided therapy, which lies on principles of the right medication for the right patient in the right dose at the right time, can significantly increase the patient’s response to symptom relief therapy in knee osteoarthritis. Corticosteroid intra-articular injections and hyaluronic acid injections provoke numerous discussions and disagreements among different guidelines, even though they are currently used in daily clinical practice. Biological options, such as platelet- rich plasma and mesenchymal stem cell injections, have shown good results in the treatment of osteoarthritis symptoms, greatly increasing the patient’s quality of life, especially when combined with other therapeutic options. Non-inclusion of the latter therapies in the guidelines, and their inconsistent stance on numerous therapy options, requires larger and well-designed studies to examine the true effects of these therapies and update the existing guidelines.

Izvorni jezik
Engleski



POVEZANOST RADA


Ustanove:
Medicinski fakultet, Rijeka,
Klinička bolnica "Sveti Duh",
KBC "Sestre Milosrdnice",
Klinička bolnica "Dubrava",
Medicinski fakultet, Split,
Opća bolnica Karlovac,
Sveučilište J. J. Strossmayera u Osijeku,
Sveučilište Sjever, Koprivnica,
Sveučilište u Splitu Sveučilišni odjel zdravstvenih studija,
Specijalna bolnica Sv. Katarina

Citiraj ovu publikaciju

Primorac, Damir; Molnar, Vilim; Matišić, Vid; Hudetz, Damir; Jeleč, Željko; Rod, Eduard; Čukelj, Fabijan; Vidović, Dinko; Vrdoljak, Trpimir; Dobričić, Borut et al.
Comprehensive Review of Knee Osteoarthritis Pharmacological Treatment and the Latest Professional Societies’ Guidelines // Pharmaceuticals, 14 (2021), 3; 205, 20 doi:10.3390 (međunarodna recenzija, članak, znanstveni)
Primorac, D., Molnar, V., Matišić, V., Hudetz, D., Jeleč, Ž., Rod, E., Čukelj, F., Vidović, D., Vrdoljak, T. & Dobričić, B. (2021) Comprehensive Review of Knee Osteoarthritis Pharmacological Treatment and the Latest Professional Societies’ Guidelines. Pharmaceuticals, 14 (3), 205, 20 doi:10.3390.
@article{article, year = {2021}, pages = {20}, DOI = {10.3390}, chapter = {205}, keywords = {knee osteoarthritis, guidelines, drug therapy, pharmacogenomics, intra-articular injections, mesenchymal stem cells}, journal = {Pharmaceuticals}, doi = {10.3390}, volume = {14}, number = {3}, issn = {1424-8247}, title = {Comprehensive Review of Knee Osteoarthritis Pharmacological Treatment and the Latest Professional Societies’ Guidelines}, keyword = {knee osteoarthritis, guidelines, drug therapy, pharmacogenomics, intra-articular injections, mesenchymal stem cells}, chapternumber = {205} }
@article{article, year = {2021}, pages = {20}, DOI = {10.3390}, chapter = {205}, keywords = {knee osteoarthritis, guidelines, drug therapy, pharmacogenomics, intra-articular injections, mesenchymal stem cells}, journal = {Pharmaceuticals}, doi = {10.3390}, volume = {14}, number = {3}, issn = {1424-8247}, title = {Comprehensive Review of Knee Osteoarthritis Pharmacological Treatment and the Latest Professional Societies’ Guidelines}, keyword = {knee osteoarthritis, guidelines, drug therapy, pharmacogenomics, intra-articular injections, mesenchymal stem cells}, chapternumber = {205} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


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