Development of Antibacterial Protective Coatings Active Against MSSA and MRSA on Biodegradable Polymers (CROSBI ID 291186)
Prilog u časopisu | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Rezić, Iva ; Majdak, Mislav ; Ljoljić Bilić, Vanja ; Pokrovac, Ivan ; Martinaga, Lela ; Somogyi Škoc, Maja ; Kosalec, Ivan ;
engleski
Development of Antibacterial Protective Coatings Active Against MSSA and MRSA on Biodegradable Polymers
In this work the in vitro antimicrobial activity of colloidal solutions of nine different commercially available nanoparticles were investigated against Staphylococcus aureus strains, both methicillin-sensitive (MSSA) and methicillin-resistant (MRSA). Research covered antimicrobial investigation of different metal and metal-oxide nanoparticles, including Ag 10 nm, Ag 40 nm, Al2O3 100 nm, Au (20 nm), Pt 4 nm, TiO2 100 nm, Y2O3 100 nm, ZnO 100 nm and ZrO2 100 nm na- noparticles. Such materials were foreseen to be applied as coatings on 3D-printed biodegradable polymers: i.e., catheters, disposable materials, hospital bedding items, disposable antimicrobial linings and bandages for chronic wounds. Therefore, the antimicrobial activity of the nanoparticles was determined by agar well diffusion assays and serial microdilution broth assays. In addition, the chromatographic characterization of elements present in trace amounts was performed as a method for tracing the nanoparticles. Moreover, the potential of preparing the rough surface of biodegradable polymers for coating with antimicrobial nanoparticles was tested by 3D-printing fused deposition methodology. The in vitro results have shown that particular nanoparticles provided powerful antimicrobial effects against MSSA and MRSA strains, and can be easily applied on different biopolymers.
antibacterial coating ; Staphylococcus aureus ; MRSA ; nanoparticles ; 3D printing ;
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Podaci o izdanju
Povezanost rada
Farmacija, Interdisciplinarne tehničke znanosti, Kemija, Kemijsko inženjerstvo, Tekstilna tehnologija