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Pregled bibliografske jedinice broj: 1112133

Chemical Composition, Antioxidant, and α-Glucosidase-Inhibiting Activity of Aqueous and Hydroethanolic Extracts of Traditional Antidiabetics from Croatian Ethnomedicine


Bljajić, Kristina; Brajković, Andrea; Čačić, Ana; Vujić, Lovorka; Jablan, Jasna; Saraiva de Carvalho, Isabel; Zovko Končić, Marijana
Chemical Composition, Antioxidant, and α-Glucosidase-Inhibiting Activity of Aqueous and Hydroethanolic Extracts of Traditional Antidiabetics from Croatian Ethnomedicine // Horticulturae, 7 (2021), 2; 15, 19 doi:10.3390/horticulturae7020015 (međunarodna recenzija, članak, ostalo)


CROSBI ID: 1112133 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Chemical Composition, Antioxidant, and α-Glucosidase-Inhibiting Activity of Aqueous and Hydroethanolic Extracts of Traditional Antidiabetics from Croatian Ethnomedicine

Autori
Bljajić, Kristina ; Brajković, Andrea ; Čačić, Ana ; Vujić, Lovorka ; Jablan, Jasna ; Saraiva de Carvalho, Isabel ; Zovko Končić, Marijana

Izvornik
Horticulturae (2311-7524) 7 (2021), 2; 15, 19

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, ostalo

Ključne riječi
chromium ; ethnopharmacology ; flavonoids ; glucose-lowering activity ; HPLC ; natural antioxidants ; polyphenol

Sažetak
Type 2 diabetes (T2D) is a chronic disease with a growing prevalence worldwide. In addition to the conventional therapy, many T2D patients use phytotherapeutic preparations. In the present study, chemical composition, antioxidant, and α-glucosidase inhibiting activity of traditional antidiabetics from Croatian ethnomedicine (Achillea millefolium, Artemisia absinthium, Centaurium erythraea, Morusalba, Phaseolus vulgaris, Sambucus nigra, and Salvia officinalis) were assessed. The efficacy of water and 80% ethanol as extraction solvents for bioactive constituents was compared. HPLC analysis revealed that the prepared extracts were rich in phenols, especially rutin, ferulic, and chlorogenic acid. Antiradical (against DPPH and ABTS radicals), reducing (towards Mo6+ and Fe3+ ions), and enzyme inhibiting properties were in linear correlation with the content of phenolic constituents. Ethanolic extracts, richer in phenolic substances, showed dominant efficacy in those assays. Aqueous extracts, on the other hand, were better Fe2+ ion chelators and more active in the β-carotene linoleic acid assay. Extracts from S. officinalis and A. millefolium were particularly active antioxidants and α-glucosidase inhibitors. A. absinthium, another potent α-glucosidase inhibitor, contained chromium, a mineral that promotes insulin action. The investigated plants contained significant amounts of minerals useful in management of T2D, with negligible amounts of heavy metals deeming them safe for human use. View Full-Text

Izvorni jezik
Engleski

Znanstvena područja
Farmacija



POVEZANOST RADA


Projekti:
IP-2018-01-6504 - Ekstrakcija bioaktivnih biljnih sastavnica pomoću zelenih otapala – korak prema zelenim kozmeceuticima (CosmoGreen) (Zovko Končić, Marijana, HRZZ - 2018-01) ( POIROT)

Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb

Citiraj ovu publikaciju

Bljajić, Kristina; Brajković, Andrea; Čačić, Ana; Vujić, Lovorka; Jablan, Jasna; Saraiva de Carvalho, Isabel; Zovko Končić, Marijana
Chemical Composition, Antioxidant, and α-Glucosidase-Inhibiting Activity of Aqueous and Hydroethanolic Extracts of Traditional Antidiabetics from Croatian Ethnomedicine // Horticulturae, 7 (2021), 2; 15, 19 doi:10.3390/horticulturae7020015 (međunarodna recenzija, članak, ostalo)
Bljajić, K., Brajković, A., Čačić, A., Vujić, L., Jablan, J., Saraiva de Carvalho, I. & Zovko Končić, M. (2021) Chemical Composition, Antioxidant, and α-Glucosidase-Inhibiting Activity of Aqueous and Hydroethanolic Extracts of Traditional Antidiabetics from Croatian Ethnomedicine. Horticulturae, 7 (2), 15, 19 doi:10.3390/horticulturae7020015.
@article{article, year = {2021}, pages = {19}, DOI = {10.3390/horticulturae7020015}, chapter = {15}, keywords = {chromium, ethnopharmacology, flavonoids, glucose-lowering activity, HPLC, natural antioxidants, polyphenol}, journal = {Horticulturae}, doi = {10.3390/horticulturae7020015}, volume = {7}, number = {2}, issn = {2311-7524}, title = {Chemical Composition, Antioxidant, and α-Glucosidase-Inhibiting Activity of Aqueous and Hydroethanolic Extracts of Traditional Antidiabetics from Croatian Ethnomedicine}, keyword = {chromium, ethnopharmacology, flavonoids, glucose-lowering activity, HPLC, natural antioxidants, polyphenol}, chapternumber = {15} }
@article{article, year = {2021}, pages = {19}, DOI = {10.3390/horticulturae7020015}, chapter = {15}, keywords = {chromium, ethnopharmacology, flavonoids, glucose-lowering activity, HPLC, natural antioxidants, polyphenol}, journal = {Horticulturae}, doi = {10.3390/horticulturae7020015}, volume = {7}, number = {2}, issn = {2311-7524}, title = {Chemical Composition, Antioxidant, and α-Glucosidase-Inhibiting Activity of Aqueous and Hydroethanolic Extracts of Traditional Antidiabetics from Croatian Ethnomedicine}, keyword = {chromium, ethnopharmacology, flavonoids, glucose-lowering activity, HPLC, natural antioxidants, polyphenol}, chapternumber = {15} }

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Emerging Sources Citation Index (ESCI)
  • Scopus


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