Pretražite po imenu i prezimenu autora, mentora, urednika, prevoditelja

Napredna pretraga

Pregled bibliografske jedinice broj: 1111810

Immunogenicity of Newcastle disease virus strain ZG1999HDS applied oculonasally or by means of nebulisation to day-old chicks


Cvetić, Željko; Nedeljković, Gordana; Jergović, Mladen; Bendelja, Krešo; Mazija, Hrvoje; Gottstein, Željko
Immunogenicity of Newcastle disease virus strain ZG1999HDS applied oculonasally or by means of nebulisation to day-old chicks // Poultry Science, 100 (2021), 4; 101001, 9 doi:10.1016/j.psj.2021.01.024 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1111810 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Immunogenicity of Newcastle disease virus strain ZG1999HDS applied oculonasally or by means of nebulisation to day-old chicks

Autori
Cvetić, Željko ; Nedeljković, Gordana ; Jergović, Mladen ; Bendelja, Krešo ; Mazija, Hrvoje ; Gottstein, Željko

Izvornik
Poultry Science (0032-5791) 100 (2021), 4; 101001, 9

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Newcastle disease ; cell-mediated immunity ; flow cytometry ; interferon-α ; interferon- γ

Sažetak
Newcastle disease (ND) is one of the classic viral infections of poultry which resists all the efforts of eradication. Newcastle disease virus (NDV) strain ZG1999HDS was isolated during the outbreak in 1, 999 at a broiler farm in Croatia. Previous trials in chickens confirmed it to be a lentogenic pathotype and immunogenic by stimulating humoral and cell mediated immunity. Further characterization by deduced amino acid sequence at the cleavage site of fusion protein confirmed its lentogenic nature, and in vitro tests its oncolytic capacity. Owing to its immunogenicity, strain ZG1999HDS is considered for vaccine development. In this study, 1-day-old chicks were vaccinated using strain ZG1999HDS oculonasally or by nebulization. Strain ZG1999HDS induced humoral immune response in both immunized groups The cell-mediated immune response occurred earlier in the group immunized by nebulization, as shown by a higher frequency rate of T and B lymphocytes, and significantly higher expression of IFN-α in respiratory organs and IFN-γ expression in the spleen. Viral genomic RNA was not detected in investigated organs. Thus, NDV strain ZG1999HDS is immunogenic when administered by means of nebulization or oculonasally without any adverse effects and is therefore suitable for further research and vaccine development. Further research is needed regarding its tropism.

Izvorni jezik
Engleski

Znanstvena područja
Biologija, Veterinarska medicina, Interdisciplinarne biotehničke znanosti



POVEZANOST RADA


Projekti:
MZOS-053-0531863-1858 - Imunoprofilaksa bolesti peradi i drugih ptica (Gottstein, Željko, MZOS ) ( POIROT)

Ustanove:
Veterinarski fakultet, Zagreb,
Sveučilište u Zagrebu

Poveznice na cjeloviti tekst rada:

doi www.sciencedirect.com

Citiraj ovu publikaciju:

Cvetić, Željko; Nedeljković, Gordana; Jergović, Mladen; Bendelja, Krešo; Mazija, Hrvoje; Gottstein, Željko
Immunogenicity of Newcastle disease virus strain ZG1999HDS applied oculonasally or by means of nebulisation to day-old chicks // Poultry Science, 100 (2021), 4; 101001, 9 doi:10.1016/j.psj.2021.01.024 (međunarodna recenzija, članak, znanstveni)
Cvetić, Ž., Nedeljković, G., Jergović, M., Bendelja, K., Mazija, H. & Gottstein, Ž. (2021) Immunogenicity of Newcastle disease virus strain ZG1999HDS applied oculonasally or by means of nebulisation to day-old chicks. Poultry Science, 100 (4), 101001, 9 doi:10.1016/j.psj.2021.01.024.
@article{article, author = {Cveti\'{c}, \v{Z}eljko and Nedeljkovi\'{c}, Gordana and Jergovi\'{c}, Mladen and Bendelja, Kre\v{s}o and Mazija, Hrvoje and Gottstein, \v{Z}eljko}, year = {2021}, pages = {9}, DOI = {10.1016/j.psj.2021.01.024}, chapter = {101001}, keywords = {Newcastle disease, cell-mediated immunity, flow cytometry, interferon-α, interferon- γ}, journal = {Poultry Science}, doi = {10.1016/j.psj.2021.01.024}, volume = {100}, number = {4}, issn = {0032-5791}, title = {Immunogenicity of Newcastle disease virus strain ZG1999HDS applied oculonasally or by means of nebulisation to day-old chicks}, keyword = {Newcastle disease, cell-mediated immunity, flow cytometry, interferon-α, interferon- γ}, chapternumber = {101001} }
@article{article, author = {Cveti\'{c}, \v{Z}eljko and Nedeljkovi\'{c}, Gordana and Jergovi\'{c}, Mladen and Bendelja, Kre\v{s}o and Mazija, Hrvoje and Gottstein, \v{Z}eljko}, year = {2021}, pages = {9}, DOI = {10.1016/j.psj.2021.01.024}, chapter = {101001}, keywords = {Newcastle disease, cell-mediated immunity, flow cytometry, interferon-α, interferon- γ}, journal = {Poultry Science}, doi = {10.1016/j.psj.2021.01.024}, volume = {100}, number = {4}, issn = {0032-5791}, title = {Immunogenicity of Newcastle disease virus strain ZG1999HDS applied oculonasally or by means of nebulisation to day-old chicks}, keyword = {Newcastle disease, cell-mediated immunity, flow cytometry, interferon-α, interferon- γ}, chapternumber = {101001} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


Citati:





    Contrast
    Increase Font
    Decrease Font
    Dyslexic Font