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Pregled bibliografske jedinice broj: 1108629

Pulsed Field Ablation in Patients With Persistent Atrial Fibrillation


Reddy, Vivek Y.; Anic, Ante; Koruth, Jacob; Petru, Jan; Funasako, Moritoshi; Minami, Kentaro; Breskovic, Toni; Sikiric, Ivan; Dukkipati, Srinivas R.; Kawamura, Iwanari; Neuzil, Petr
Pulsed Field Ablation in Patients With Persistent Atrial Fibrillation // Journal of the American College of Cardiology, 76 (2020), 9; 1068-1080 doi:10.1016/j.jacc.2020.07.007 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1108629 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Pulsed Field Ablation in Patients With Persistent Atrial Fibrillation

Autori
Reddy, Vivek Y. ; Anic, Ante ; Koruth, Jacob ; Petru, Jan ; Funasako, Moritoshi ; Minami, Kentaro ; Breskovic, Toni ; Sikiric, Ivan ; Dukkipati, Srinivas R. ; Kawamura, Iwanari ; Neuzil, Petr

Izvornik
Journal of the American College of Cardiology (0735-1097) 76 (2020), 9; 1068-1080

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
catheter ablation ; esophagus ; persistent atrial fibrillation ; posterior wall ; pulmonary vein isolation ; pulsed field ablation

Sažetak
Background: Unlike for paroxysmal atrial fibrillation (AF), pulmonary vein isolation (PVI) alone is considered insufficient for many patients with persistent AF. Adjunctive ablation of the left atrial posterior wall (LAPW) may improve outcomes, but is limited by both the difficulty of achieving lesion durability and concerns of damage to the esophagus-situated behind the LAPW. Objectives: This study sought to assess the safety and lesion durability of pulsed field ablation (PFA) for both PVI and LAPW ablation in persistent AF. Methods: PersAFOne is a single-arm study evaluating biphasic, bipolar PFA using a multispline catheter for PVI and LAPW ablation under intracardiac echocardiographic guidance. A focal PFA catheter was used for cavotricuspid isthmus ablation. No esophageal protection strategy was used. Invasive remapping was mandated at 2 to 3 months to assess lesion durability. Results: In 25 patients, acute PVI (96 of 96 pulmonary veins [PVs] ; mean ablation time: 22 min ; interquartile range [IQR]: 15 to 29 min) and LAPW ablation (24 of 24 patients ; median ablation time: 10 min ; IQR: 6 to 13 min) were 100% acutely successful with the multispline PFA catheter alone. Using the focal PFA catheter, acute cavotricuspid isthmus block was achieved in 13 of 13 patients (median: 9 min ; IQR: 6 to 12 min). The median total procedure time was 125 min (IQR: 108 to 166 min) (including a median of 28 min [IQR: 25 to 33 min] for voltage mapping), with a median of 16 min (IQR: 12 to 23 min) fluoroscopy. Post- procedure esophagogastroduodenoscopy and repeat cardiac computed tomography revealed no mucosal lesions or PV narrowing, respectively. Invasive remapping demonstrated durable isolation (defined by entrance block) in 82 of 85 PVs (96%) and 21 of 21 LAPWs (100%) treated with the pentaspline catheter. In 3 patients, there was localized scar regression of the LAPW ablation, albeit without conduction breakthrough. Conclusions: The unique safety profile of PFA potentiated efficient, safe, and durable PVI and LAPW ablation. This extends the potential role of PFA beyond paroxysmal to persistent forms of AF. (Pulsed Fields for Persistent Atrial Fibrillation [PersAFOne] ; NCT04170621).

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove:
KBC Split

Profili:

Avatar Url Toni Brešković (autor)

doi

Citiraj ovu publikaciju

Reddy, Vivek Y.; Anic, Ante; Koruth, Jacob; Petru, Jan; Funasako, Moritoshi; Minami, Kentaro; Breskovic, Toni; Sikiric, Ivan; Dukkipati, Srinivas R.; Kawamura, Iwanari; Neuzil, Petr
Pulsed Field Ablation in Patients With Persistent Atrial Fibrillation // Journal of the American College of Cardiology, 76 (2020), 9; 1068-1080 doi:10.1016/j.jacc.2020.07.007 (međunarodna recenzija, članak, znanstveni)
Reddy, V., Anic, A., Koruth, J., Petru, J., Funasako, M., Minami, K., Breskovic, T., Sikiric, I., Dukkipati, S., Kawamura, I. & Neuzil, P. (2020) Pulsed Field Ablation in Patients With Persistent Atrial Fibrillation. Journal of the American College of Cardiology, 76 (9), 1068-1080 doi:10.1016/j.jacc.2020.07.007.
@article{article, year = {2020}, pages = {1068-1080}, DOI = {10.1016/j.jacc.2020.07.007}, keywords = {catheter ablation, esophagus, persistent atrial fibrillation, posterior wall, pulmonary vein isolation, pulsed field ablation}, journal = {Journal of the American College of Cardiology}, doi = {10.1016/j.jacc.2020.07.007}, volume = {76}, number = {9}, issn = {0735-1097}, title = {Pulsed Field Ablation in Patients With Persistent Atrial Fibrillation}, keyword = {catheter ablation, esophagus, persistent atrial fibrillation, posterior wall, pulmonary vein isolation, pulsed field ablation} }
@article{article, year = {2020}, pages = {1068-1080}, DOI = {10.1016/j.jacc.2020.07.007}, keywords = {catheter ablation, esophagus, persistent atrial fibrillation, posterior wall, pulmonary vein isolation, pulsed field ablation}, journal = {Journal of the American College of Cardiology}, doi = {10.1016/j.jacc.2020.07.007}, volume = {76}, number = {9}, issn = {0735-1097}, title = {Pulsed Field Ablation in Patients With Persistent Atrial Fibrillation}, keyword = {catheter ablation, esophagus, persistent atrial fibrillation, posterior wall, pulmonary vein isolation, pulsed field ablation} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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