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Pregled bibliografske jedinice broj: 1106854

Factor X Deficiency Management for Elective Cesarean Delivery in a Pregnant Patient


Krkovic, Mirna; Koosova Gajic, Andrea; Tarčuković, Janja; Sotosek, Vlatka; Stimac, Tea; Balen, Sanja; Dangubic, Boban; Grubjesic, Igor
Factor X Deficiency Management for Elective Cesarean Delivery in a Pregnant Patient // American Journal of Case Reports, 21 (2020), 1-6 doi:10.12659/ajcr.920685 (međunarodna recenzija, članak, znanstveni)


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Naslov
Factor X Deficiency Management for Elective Cesarean Delivery in a Pregnant Patient

Autori
Krkovic, Mirna ; Koosova Gajic, Andrea ; Tarčuković, Janja ; Sotosek, Vlatka ; Stimac, Tea ; Balen, Sanja ; Dangubic, Boban ; Grubjesic, Igor

Izvornik
American Journal of Case Reports (1941-5923) 21 (2020); 1-6

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
Factor X Deficiency • Pregnancy Complications, Hematologic • Pregnancy, High-Risk

Sažetak
BACKGROUND: Congenital factor X deficiency is a rare inherited coagulopathy. Pregnancies in women with this disorder are often associated with adverse outcomes, including miscarriage, premature labor, and hemorrhage during pregnancy and in the peripartum period. The literature on this disorder is sparse and shows a limited number of successful pregnancies in women with factor X deficiency. CASE REPORT: In this report, we present the case of a successful pregnancy and term delivery by elective cesarean section in a 39- year-old primigravida with congenital factor X deficiency. Medical management followed the recommendations of an interdisciplinary team comprising specialists in obstetrics, anesthesia, transfusion medicine, hematology, and neonatology. This high-risk pregnancy was successfully brought to term, and a healthy male neonate was delivered by elective cesarean section at 39 weeks’ gestation. The patient’s factor X deficiency (0.19 kIU/L) was treated using 4 units of solvent-detergent-treated fresh frozen plasma (SD-FFP) 1 h before the cesarean section, leading to hemostatic levels of factor X and an uneventful intraoperative course. Postoperatively, the patient’s factor X levels were controlled daily and corrected using SD-FFP as needed, with no clinically significant blood loss. CONCLUSIONS: SD-FFP can be used to manage congenital factor X deficiency in the peripartum period and maintain perioperative blood loss within normal limits.

Izvorni jezik
Engleski

Znanstvena područja
Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove:
Medicinski fakultet, Rijeka,
Klinički bolnički centar Rijeka

Poveznice na cjeloviti tekst rada:

doi www.amjcaserep.com

Citiraj ovu publikaciju:

Krkovic, Mirna; Koosova Gajic, Andrea; Tarčuković, Janja; Sotosek, Vlatka; Stimac, Tea; Balen, Sanja; Dangubic, Boban; Grubjesic, Igor
Factor X Deficiency Management for Elective Cesarean Delivery in a Pregnant Patient // American Journal of Case Reports, 21 (2020), 1-6 doi:10.12659/ajcr.920685 (međunarodna recenzija, članak, znanstveni)
Krkovic, M., Koosova Gajic, A., Tarčuković, J., Sotosek, V., Stimac, T., Balen, S., Dangubic, B. & Grubjesic, I. (2020) Factor X Deficiency Management for Elective Cesarean Delivery in a Pregnant Patient. American Journal of Case Reports, 21, 1-6 doi:10.12659/ajcr.920685.
@article{article, year = {2020}, pages = {1-6}, DOI = {10.12659/ajcr.920685}, keywords = {Factor X Deficiency • Pregnancy Complications, Hematologic • Pregnancy, High-Risk}, journal = {American Journal of Case Reports}, doi = {10.12659/ajcr.920685}, volume = {21}, issn = {1941-5923}, title = {Factor X Deficiency Management for Elective Cesarean Delivery in a Pregnant Patient}, keyword = {Factor X Deficiency • Pregnancy Complications, Hematologic • Pregnancy, High-Risk} }
@article{article, year = {2020}, pages = {1-6}, DOI = {10.12659/ajcr.920685}, keywords = {Factor X Deficiency • Pregnancy Complications, Hematologic • Pregnancy, High-Risk}, journal = {American Journal of Case Reports}, doi = {10.12659/ajcr.920685}, volume = {21}, issn = {1941-5923}, title = {Factor X Deficiency Management for Elective Cesarean Delivery in a Pregnant Patient}, keyword = {Factor X Deficiency • Pregnancy Complications, Hematologic • Pregnancy, High-Risk} }

Časopis indeksira:


  • Web of Science Core Collection (WoSCC)
    • Emerging Sources Citation Index (ESCI)
  • Scopus
  • MEDLINE


Citati:





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