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Etiologic Index — A Case-Only Measure of BRCA1/2– Associated Cancer Risk (CROSBI ID 288959)
Prilog u časopisu | Pismo uredniku | međunarodna recenzija
Hughley, Raymond ; Karlic, Rosa ; Joshi, Himanshu ; Turnbull, Clare ; Foulkes, William D. ; Polak, Paz
Etiologic Index — A Case-Only Measure of BRCA1/2– Associated Cancer Risk // The New England journal of medicine, 383 (2020), 3; 286-288. doi: 10.1056/nejmc1913988
Podaci o odgovornosti
Hughley, Raymond ; Karlic, Rosa ; Joshi, Himanshu ; Turnbull, Clare ; Foulkes, William D. ; Polak, Paz
engleski
Etiologic Index — A Case-Only Measure of BRCA1/2– Associated Cancer Risk
Description of the development of Etiologic Index of BRCA1 and BRCA2, a proposed etiologic index, based on genomic variation in tumor cells and matched normal cells, that can be used to evaluate the relevance of germline pathogenic variants (GPVs) in tumor-suppressor genes to the development of individual cancer types.
cancer risk ; epidemiology
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