engleski

Metastatic tumors to the jawbones - report of 10 cases

Introduction: Metastatic tumors to the jaw bones are rare and usually develop during the final stages of cancer. Some cancers such as lung, breast and kidney cancers are prone to the jaw metastases. Objectives: To analyze clinical and epidemiologic characteristic of patients with metastatic tumor to the jawbones. Materials and Methos: We retrieved patients' charts from 4478 patients with metastatic tumor during the period of 15 years who were treated in the Clinical Hospital Centre Dubrava in Zagreb, Croatia. A retrospective analysis was made of patient age, gender, primary tumor location, localization and clinical presentation of the jaw metastasis, time interval from diagnosis of primary tumor and oral metastasis and time interval from diagnosis of oral metastasis to death. Results: There were 4 male and 6 female patients (mean age, 56.7 years). Out of 10 patients diagnosed with jaw metastases, the most common primary tumours were kidney (n=5), lung (n=2), breast (n=1), colon (n=1) and unknown primary tumor (n=1). The mandible was more often affected (n=7) than maxilla (n=3). The most common histological type was adenocarcinoma (n=6). In the most of the patients (n=7) the primary tumor was diagnosed before the oral metastatic lesion. Jaw metastasis was the first sign of metastatic tumor in 3 patients and 1 was diagnosed at the same time as primary tumor. Most of the patients had some oral difficulties. Follow up period varied between the patients. Conclusion: Due to the rare presentation, the diagnosis of a metastatic lesions in the oral region remains challenging.

metastatic tumors ; jawbones ; epidemiologic characteristic

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