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Erythromycin Series. Part 13. Synthesis and structure elucidation of 10-dihydro-10-deoxo-11-methyl-11-azaerythromycin A

10-dihydro-10- deoxo-11-methyl-11- azaerythromycin A, known as DCH3, XZ-450, or CP-62, 993, is a promising new semisynthetic macrolide antibiotic with an enhanced antibacterial spectrum, a longer half-life, and greater tissue penetration than erythromycin A it self. It is now undergoing clinical development the generic name azithromycin.

azithromycin ; synthesis ; structure

J. Chem. Research (M); 1239.-1261.