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Pregled bibliografske jedinice broj: 1099604

Busulfan-Induced Lung Injury in Pediatric Oncology Patients—Review of the Literature with an Illustrative Case


Matijasic, Nusa; Bonevski, Aleksandra; Tokic Pivac, Visnja; Pavic, Ivan
Busulfan-Induced Lung Injury in Pediatric Oncology Patients—Review of the Literature with an Illustrative Case // Pediatric Allergy, Immunology, and Pulmonology, 32 (2019), 3; 86-91 doi:10.1089/ped.2019.0990 (međunarodna recenzija, članak, ostalo)


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Naslov
Busulfan-Induced Lung Injury in Pediatric Oncology Patients—Review of the Literature with an Illustrative Case

Autori
Matijasic, Nusa ; Bonevski, Aleksandra ; Tokic Pivac, Visnja ; Pavic, Ivan

Izvornik
Pediatric Allergy, Immunology, and Pulmonology (2151-321X) 32 (2019), 3; 86-91

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, ostalo

Ključne riječi
busulfan, lung injury, interstitial lung disease

Sažetak
Background: Impaired lung function has been detected in up to 65% of all childhood cancer survivors. It is often caused by exposure to radiation therapy and various chemotherapeutics. The first cytotoxic drug ever identified as a causative agent of lung injury was busulfan, reported in the early 1960s. Signs and symptoms of busulfan lung are nonspecific and it is therefore difficult to differentiate the condition from pulmonary impairment caused by other pulmotoxic agents, infections, pulmonary metastases, graft-versus- host disease, or other noninfectious post- transplant complications involving the lungs. Methods: A case example is provided to illustrate the difficulties in management of busulfan-induced lung injury in children. A retrospective review of cases of busulfan- induced lung injury indexed in PubMed until March 2019 was performed. Inclusion criteria for articles was available in full text in English. Results: Impaired lung function caused by busulfan may become an increasing problem for young survivors. Conclusion: Newly developed dyspnea or subclinical damage detected on pulmonary function tests, indicating primarily restrictive disease, should always arouse suspicion of busulfan-induced lung injury in a child conditioned with busulfan, especially after excluding other leading culprits of pulmonary damage affecting oncology patients.

Izvorni jezik
Engleski



POVEZANOST RADA


Ustanove:
Medicinski fakultet, Split,
Klinika za dječje bolesti

Profili:

Avatar Url Ivan Pavić (autor)

Avatar Url Aleksandra Bonevski (autor)

doi

Citiraj ovu publikaciju

Matijasic, Nusa; Bonevski, Aleksandra; Tokic Pivac, Visnja; Pavic, Ivan
Busulfan-Induced Lung Injury in Pediatric Oncology Patients—Review of the Literature with an Illustrative Case // Pediatric Allergy, Immunology, and Pulmonology, 32 (2019), 3; 86-91 doi:10.1089/ped.2019.0990 (međunarodna recenzija, članak, ostalo)
Matijasic, N., Bonevski, A., Tokic Pivac, V. & Pavic, I. (2019) Busulfan-Induced Lung Injury in Pediatric Oncology Patients—Review of the Literature with an Illustrative Case. Pediatric Allergy, Immunology, and Pulmonology, 32 (3), 86-91 doi:10.1089/ped.2019.0990.
@article{article, year = {2019}, pages = {86-91}, DOI = {10.1089/ped.2019.0990}, keywords = {busulfan, lung injury, interstitial lung disease}, journal = {Pediatric Allergy, Immunology, and Pulmonology}, doi = {10.1089/ped.2019.0990}, volume = {32}, number = {3}, issn = {2151-321X}, title = {Busulfan-Induced Lung Injury in Pediatric Oncology Patients—Review of the Literature with an Illustrative Case}, keyword = {busulfan, lung injury, interstitial lung disease} }
@article{article, year = {2019}, pages = {86-91}, DOI = {10.1089/ped.2019.0990}, keywords = {busulfan, lung injury, interstitial lung disease}, journal = {Pediatric Allergy, Immunology, and Pulmonology}, doi = {10.1089/ped.2019.0990}, volume = {32}, number = {3}, issn = {2151-321X}, title = {Busulfan-Induced Lung Injury in Pediatric Oncology Patients—Review of the Literature with an Illustrative Case}, keyword = {busulfan, lung injury, interstitial lung disease} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


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