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Pregled bibliografske jedinice broj: 1098513

Assessment of the Biological Activity and Phenolic Composition of Ethanol Extracts of Pomegranate (Punica granatum L.) Peels


Peršurić, Željka; Saftić Martinović, Lara; Malenica, Mladenka; Gobin, Ivana; Pedisić, Sandra; Dragović-Uzelac, Verica; Kraljević Pavelić, Sandra
Assessment of the Biological Activity and Phenolic Composition of Ethanol Extracts of Pomegranate (Punica granatum L.) Peels // Molecules, 25 (2020), 24; 5916, 13 doi:10.3390/molecules25245916 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1098513 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Assessment of the Biological Activity and Phenolic Composition of Ethanol Extracts of Pomegranate (Punica granatum L.) Peels

Autori
Peršurić, Željka ; Saftić Martinović, Lara ; Malenica, Mladenka ; Gobin, Ivana ; Pedisić, Sandra ; Dragović-Uzelac, Verica ; Kraljević Pavelić, Sandra

Izvornik
Molecules (1420-3049) 25 (2020), 24; 5916, 13

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
phytochemicals ; pomegranate peel ; antioxidant activity ; antibacterial activity ; antiproliferative activity

Sažetak
Pomegranate (Punica granatum L.) is a rich source of constituents with confirmed strong biological activities. However, pomegranate peel, which encompasses approximately 30–40% of its weight, is treated as a biological waste. The aim of this paper was to evaluate the potential of pomegranate peel extracts and to propose its functional properties that can be used for development of functional products. Eight ethanol extracts of pomegranate peels (PPEs) were characterized by use of direct infusion quadrupole-time of flight (Q-TOF), and afterwards tested on their antioxidant, antibacterial and antiproliferative activities. Mass spectrometry analysis revealed that the most prevalent compounds in pomegranate peels were punicalagin, granatin and their derivatives. Analysed extracts had high total phenolic contents that ranged from 5766.44 to 10599.43 mg GAE/100 g, and strong antioxidant activity (7551.31–7875.42 and 100.25– 176.60 μmol TE/100 g for DPPH and FRAP assays, respectively). The results of biological activity assays showed that all PPEs possessed antibacterial activity, and that S. aureus was the most sensitive specie with minimum inhibitory concentration and minimum bactericidal concentrations ranging from 0.8 to 6.4 mg/mL. Additionally, the analysis of antiproliferative activity revealed high potency of PPEs, as the IC50 values ranged from 0.132 mg/mL to 0.396 mg/mL. Multivariate analysis pointed out the most discriminative metabolites for antioxidant or antiproliferative activity. Overall, the pomegranate peel confirmed to be a highly valuable source of bioactive compounds that could be used to improve the food functional characteristics

Izvorni jezik
Engleski

Znanstvena područja
Prehrambena tehnologija, Nutricionizam, Biotehnologija u biomedicini (prirodno područje, biomedicina i zdravstvo, biotehničko područje)



POVEZANOST RADA


Projekti:
EK-KF-KK.01.1.1.01.0002 - Bioprospecting Jadranskog mora (Čož-Rakovac, Rozelinda; Dragović-Uzelac, Verica; Šantek, Božidar; Jokić, Stela; Jerković, Igor; Kraljević Pavelić, Sandra, EK - KK.01.1.1.01) ( POIROT)

Ustanove:
Prehrambeno-biotehnološki fakultet, Zagreb,
Medicinski fakultet, Rijeka,
Sveučilište u Rijeci - Odjel za biotehnologiju,
Fakultet zdravstvenih studija u Rijeci

Citiraj ovu publikaciju

Peršurić, Željka; Saftić Martinović, Lara; Malenica, Mladenka; Gobin, Ivana; Pedisić, Sandra; Dragović-Uzelac, Verica; Kraljević Pavelić, Sandra
Assessment of the Biological Activity and Phenolic Composition of Ethanol Extracts of Pomegranate (Punica granatum L.) Peels // Molecules, 25 (2020), 24; 5916, 13 doi:10.3390/molecules25245916 (međunarodna recenzija, članak, znanstveni)
Peršurić, Ž., Saftić Martinović, L., Malenica, M., Gobin, I., Pedisić, S., Dragović-Uzelac, V. & Kraljević Pavelić, S. (2020) Assessment of the Biological Activity and Phenolic Composition of Ethanol Extracts of Pomegranate (Punica granatum L.) Peels. Molecules, 25 (24), 5916, 13 doi:10.3390/molecules25245916.
@article{article, year = {2020}, pages = {13}, DOI = {10.3390/molecules25245916}, chapter = {5916}, keywords = {phytochemicals, pomegranate peel, antioxidant activity, antibacterial activity, antiproliferative activity}, journal = {Molecules}, doi = {10.3390/molecules25245916}, volume = {25}, number = {24}, issn = {1420-3049}, title = {Assessment of the Biological Activity and Phenolic Composition of Ethanol Extracts of Pomegranate (Punica granatum L.) Peels}, keyword = {phytochemicals, pomegranate peel, antioxidant activity, antibacterial activity, antiproliferative activity}, chapternumber = {5916} }
@article{article, year = {2020}, pages = {13}, DOI = {10.3390/molecules25245916}, chapter = {5916}, keywords = {phytochemicals, pomegranate peel, antioxidant activity, antibacterial activity, antiproliferative activity}, journal = {Molecules}, doi = {10.3390/molecules25245916}, volume = {25}, number = {24}, issn = {1420-3049}, title = {Assessment of the Biological Activity and Phenolic Composition of Ethanol Extracts of Pomegranate (Punica granatum L.) Peels}, keyword = {phytochemicals, pomegranate peel, antioxidant activity, antibacterial activity, antiproliferative activity}, chapternumber = {5916} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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