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Pregled bibliografske jedinice broj: 1096709

Food (Matrix) Effects on Bioaccessibility and Intestinal Permeability of Major Olive Antioxidants


Vitali Čepo, Dubravka; Radić, Kristina; Turčić, Petra; Anić, Dora; Komar, Barbara; Šalov, Mirela
Food (Matrix) Effects on Bioaccessibility and Intestinal Permeability of Major Olive Antioxidants // Foods, 9 (2020), 1831; 1-17 doi:10.3390/foods9121831 (međunarodna recenzija, članak, znanstveni)


CROSBI ID: 1096709 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Food (Matrix) Effects on Bioaccessibility and Intestinal Permeability of Major Olive Antioxidants

Autori
Vitali Čepo, Dubravka ; Radić, Kristina ; Turčić, Petra ; Anić, Dora ; Komar, Barbara ; Šalov, Mirela

Izvornik
Foods (2304-8158) 9 (2020), 1831; 1-17

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, znanstveni

Ključne riječi
olive pomace ; hydroxytyrosol ; tyrosol ; polyphenol-food interaction ; Caco-2 monolayer ; in vitro digestion

Sažetak
Background: olive pomace extract (OPE) is a rich source of health promoting polyphenols (hydroxytyrosol (HTS) and tyrosol (TS)) and can be used as a nutraceutical ingredient of dietary supplements and functional foods. Its adequate bioavailability is a prerequisite for excreting biological activity and can be significantly and specifically affected by different food matrices. Methods: in order to investigate food effects on polyphenol bioaccessibility, OPE was co-digested with different foods according to internationally harmonized in vitro digestibility method. Impact of particular nutrients on HTS and TS permeability was assessed on Caco-2 cell monolayer. Results: HTS and TS bioaccessibility and transepithelial permeability can be significantly affected by foods (nutrients), especially by casein and certain types of dietary fiber. Those effects are polyphenol-and nutrient-specific and are achieved either through complexation in gastrointestinal lumen and/or through direct effects of nutrients on intestinal monolayer. Conclusions: obtained results emphasize the significance and complexity of polyphenol interactions within the food matrix and the necessity of individual investigational approaches with respect to particular food/nutrient and interacting phenolic compounds.

Izvorni jezik
Engleski

Znanstvena područja
Farmacija



POVEZANOST RADA


Projekti:
UIP-2014-09-9143 - Održivi razvoj inovacije u hrani-valorizacija otpada masline (NutriOliWa) (Vitali Čepo, Dubravka, HRZZ - 2014-09) ( POIROT)

Ustanove:
Farmaceutsko-biokemijski fakultet, Zagreb

doi

Citiraj ovu publikaciju

Vitali Čepo, Dubravka; Radić, Kristina; Turčić, Petra; Anić, Dora; Komar, Barbara; Šalov, Mirela
Food (Matrix) Effects on Bioaccessibility and Intestinal Permeability of Major Olive Antioxidants // Foods, 9 (2020), 1831; 1-17 doi:10.3390/foods9121831 (međunarodna recenzija, članak, znanstveni)
Vitali Čepo, D., Radić, K., Turčić, P., Anić, D., Komar, B. & Šalov, M. (2020) Food (Matrix) Effects on Bioaccessibility and Intestinal Permeability of Major Olive Antioxidants. Foods, 9 (1831), 1-17 doi:10.3390/foods9121831.
@article{article, year = {2020}, pages = {1-17}, DOI = {10.3390/foods9121831}, keywords = {olive pomace, hydroxytyrosol, tyrosol, polyphenol-food interaction, Caco-2 monolayer, in vitro digestion}, journal = {Foods}, doi = {10.3390/foods9121831}, volume = {9}, number = {1831}, issn = {2304-8158}, title = {Food (Matrix) Effects on Bioaccessibility and Intestinal Permeability of Major Olive Antioxidants}, keyword = {olive pomace, hydroxytyrosol, tyrosol, polyphenol-food interaction, Caco-2 monolayer, in vitro digestion} }
@article{article, year = {2020}, pages = {1-17}, DOI = {10.3390/foods9121831}, keywords = {olive pomace, hydroxytyrosol, tyrosol, polyphenol-food interaction, Caco-2 monolayer, in vitro digestion}, journal = {Foods}, doi = {10.3390/foods9121831}, volume = {9}, number = {1831}, issn = {2304-8158}, title = {Food (Matrix) Effects on Bioaccessibility and Intestinal Permeability of Major Olive Antioxidants}, keyword = {olive pomace, hydroxytyrosol, tyrosol, polyphenol-food interaction, Caco-2 monolayer, in vitro digestion} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus


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