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Pregled bibliografske jedinice broj: 1095561

Bone health of patients with COPD in relation to their exercise capacity and gait speed


Matković, Zinka; Cvetko, Danijel; Rahelić, Dario; Esquinas, Cristina; Žarak, Marko; Tudorić, Neven; Miravitlles, Marc
Bone health of patients with COPD in relation to their exercise capacity and gait speed // European Respiratory Journal 2019 54: PA3900
Madrid, Španjolska: European Respiratory Society, 2019. 17180, 1 doi:10.1183/13993003.congress-2019.pa3900 (poster, međunarodna recenzija, sažetak, stručni)


CROSBI ID: 1095561 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Bone health of patients with COPD in relation to their exercise capacity and gait speed

Autori
Matković, Zinka ; Cvetko, Danijel ; Rahelić, Dario ; Esquinas, Cristina ; Žarak, Marko ; Tudorić, Neven ; Miravitlles, Marc

Vrsta, podvrsta i kategorija rada
Sažeci sa skupova, sažetak, stručni

Izvornik
European Respiratory Journal 2019 54: PA3900 / - Madrid, Španjolska : European Respiratory Society, 2019

Skup
ERS International Congress

Mjesto i datum
Madrid, Španjolska, 28.9. - 2.10.2019

Vrsta sudjelovanja
Poster

Vrsta recenzije
Međunarodna recenzija

Ključne riječi
Osteoporosis, COPD, osteopenia, bone mineral density, vitamin D deficiency

Sažetak
Background: Osteoporosis is an important extra- pulmonary manifestation of chronic obstructive pulmonary disease (COPD). Aim: To evaluate the prevalence of osteoporosis, osteopenia and vitamin D deficiency in patients with moderate to very severe COPD, and to explore the association between bone mineral density (BMD) and exercise capacity / gait speed. Methods: BMD and T-score were measured by the dual energy X-ray absorptiometry, and serum level of 25-hydroxyvitamin D was determined. Severity of COPD was evaluated by the pulmonary functions tests, COPD Assessment Test, and modified Medical Research dyspnoea scale. Six- minute walk distance (6MWD) and 4-metre gait speed (4MGS) test were used in the assessment of physical fitness. Results: In 111 patients (male 76, mean age 68 years, forced expiratory volume in 1 second 48.9±15 % predicted) the mean BMD was 1.1±0.1 g/cm2, and T-score -1.0±1.5. Osteoporosis (T- score <-2.5) was established in 14 patients (12.6%), and osteopenia (T-score of -1 to -2.5) in 45 patients (40.5%). Vitamin D insufficiency (serum concentration 50-75 nmol/L) was found in 105 patients (94.6%) with 86 (77.5%) being vitamin D deficient (<50 nmol/L). Patients with reduced exercise capacity (6MWD ≤350m) had significantly lower BMD (1.07±0.1 g/cm2, p=0.002) and smaller T-score (-1.4±1.4, p=0.013). Similarly, BMD and T-score were also significantly lower in patients with slow gait speed (4MGS <0.8 m/s), 1.05±0.1 g/cm2 (p=0.002) and -1.5±1.4 (p=0.017), respectively. Conclusion: High proportion of COPD patients have reduced BMD and low vitamin D levels. Poor bone health is associated with impaired physical performance.

Izvorni jezik
Engleski

Znanstvena područja
Temeljne medicinske znanosti, Kliničke medicinske znanosti



POVEZANOST RADA


Ustanove:
Klinička bolnica "Dubrava"

Profili:

Avatar Url Marko Žarak (autor)

Avatar Url Neven Tudorić (autor)

Avatar Url Dario Rahelić (autor)

Citiraj ovu publikaciju

Matković, Zinka; Cvetko, Danijel; Rahelić, Dario; Esquinas, Cristina; Žarak, Marko; Tudorić, Neven; Miravitlles, Marc
Bone health of patients with COPD in relation to their exercise capacity and gait speed // European Respiratory Journal 2019 54: PA3900
Madrid, Španjolska: European Respiratory Society, 2019. 17180, 1 doi:10.1183/13993003.congress-2019.pa3900 (poster, međunarodna recenzija, sažetak, stručni)
Matković, Z., Cvetko, D., Rahelić, D., Esquinas, C., Žarak, M., Tudorić, N. & Miravitlles, M. (2019) Bone health of patients with COPD in relation to their exercise capacity and gait speed. U: European Respiratory Journal 2019 54: PA3900 doi:10.1183/13993003.congress-2019.pa3900.
@article{article, year = {2019}, pages = {1}, DOI = {10.1183/13993003.congress-2019.pa3900}, chapter = {17180}, keywords = {Osteoporosis, COPD, osteopenia, bone mineral density, vitamin D deficiency}, doi = {10.1183/13993003.congress-2019.pa3900}, title = {Bone health of patients with COPD in relation to their exercise capacity and gait speed}, keyword = {Osteoporosis, COPD, osteopenia, bone mineral density, vitamin D deficiency}, publisher = {European Respiratory Society}, publisherplace = {Madrid, \v{S}panjolska}, chapternumber = {17180} }
@article{article, year = {2019}, pages = {1}, DOI = {10.1183/13993003.congress-2019.pa3900}, chapter = {17180}, keywords = {Osteoporosis, COPD, osteopenia, bone mineral density, vitamin D deficiency}, doi = {10.1183/13993003.congress-2019.pa3900}, title = {Bone health of patients with COPD in relation to their exercise capacity and gait speed}, keyword = {Osteoporosis, COPD, osteopenia, bone mineral density, vitamin D deficiency}, publisher = {European Respiratory Society}, publisherplace = {Madrid, \v{S}panjolska}, chapternumber = {17180} }

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