engleski

Physical and social anhedonia are associated with suicidality in major depression, but not in schizophrenia

Objective This cross-sectional study investigated the association of physical and social anhedonia with suicidality in patients with major depressive disorder (MDD), schizophrenia and in non-psychiatric controls. Method All participants completed the revised Physical Anhedonia Scale (RPAS) and the revised Social Anhedonia Scale (RSAS), and were subdivided according to positive suicidal attempt history. MDD patients were evaluated with the Montgomery-Åsberg Depression Rating Scale (MADRS), healthy respondents with the Patient Health Questionnaire-9 (PHQ-9), and schizophrenia patients with the Calgary Depression Scale for Schizophrenia (CDSS). Results In 683 study participants, the prevalence of both anhedonia was the highest in MDD, followed by schizophrenia, and the lowest in control group. Among MDD patients, those with physical and social anhedonia had greater current suicidal ideation, while higher frequency of individuals with previous suicidal attempts was detected in those with social anhedonia. In contrast, no association between either anhedonia and past suicidal attempts or current suicidal ideation was found in patients with schizophrenia. Conclusions Assessing social and physical anhedonia might be important in MDD patients, given its association with both previous and current suicidality. Suicidality in schizophrenia, while unrelated to anhedonia, might include other risk factors

anhedonia ; suicidal attempts ; suicidal thoughts ; depression ; schizophrenia

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