Functionalization of Titanium Surface by Innovative Anticorrosion Coating (CROSBI ID 695859)
Prilog sa skupa u zborniku | sažetak izlaganja sa skupa | međunarodna recenzija
Podaci o odgovornosti
Katić, Jozefina ; Šarić, Ankica ; Despotović, Ines ; Petković, Marin ; Petrović, Željka
engleski
Functionalization of Titanium Surface by Innovative Anticorrosion Coating
Since implantation success strongly depends on the osseointegration process, current trends in dental implant research are based on surface properties modifications by biomimetic and bioactive coatings that mimic biochemical surroundings and architecture of the human bone. Calcium phosphate ceramics, like hydroxyapatite, with mineral composition similar to natural bone, as a single compound coating or as a composite with collagen, bioglass, or silica are used to promote osseointegration or overall implant system’s characteristics. Drug-based coatings with bisphosphonates like Zolendronate or Alendronate, drugs for bone diseases, promote mechanical fixation of implant and bone mineralization. However, it must not be forgotten that a fundamental prerequisite for the success of osseointegration is a long-term corrosion stability of implant materials. Human body fluids, especially oral cavity fluids, in which pH is constantly changing, represent very aggressive media with high concentrations of chloride ions that are among the most aggressive and corrosive to metals. Although titanium is a gold standard in dental implantology due to its exceptional biocompatibility and corrosion resistivity, there is an increasing data reported regarding complications caused by titanium dental implant fixation. It was shown that titanium ions, that originated as product from corrosion reaction in body fluids, caused negative immune reactions or skin allergies immediately or shortly after implant fixation. Therefore, it is crucial to design a coating which will make titanium surface more bioactive/osseoinductive and at the same time more corrosion resistant during a long-term exposure to oral cavity fluids. In this study the titanium surface was modified by vitamin D3, molecules that are crucial for maintaining bone mineral density and normal functioning of the immune system. The main goals were (i) to improve titanium corrosion resistivity during exposure to an artificial saliva solution and simultaneously (ii) to induce in vitro processes of “new bone” formation. According to results of all techniques, the D3 vitamin layer imparted very good corrosion protection to the oxide-covered titanium and induced a formation of biocompatible bone-like calcium phosphates what confirmed enhanced titanium's bioactivity level.
titanium ; bioactive coating ; anticorrosion properties
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Podaci o prilogu
1211-1211.
2020.
objavljeno
Podaci o matičnoj publikaciji
71st Annual Meeting ISE, Book of Abstracts
Podaci o skupu
71st Annual Meeting of the International Society of Electrochemistry (ISE 2020)
poster
31.08.2020-04.09.2020
online