engleski

Prediction score for complications after colorectal cancer surgery based on neutrophils/lymphocytes ratio, percentage of immature granulocytes, IG and IT ratios

Introduction: The markers of inflammations are a significant predictor of postoperative outcome after colorectal cancer surgery. Along with leukocytes, C-reactive protein (CRP), procalcitonin (PCT) and neutrophil/lymphocyte ratio (NLR) we tried to test the role of immature granulocytes (IG) counts and trends in the postoperative period. Methods: We recorded matched three patient according to their sex, age, and tumor localization who had an uneventful recovery with three patients who had an anastomotic leak required reoperation. We obtained the IG count with every complete blood count and correlated these with CRP, PCT, NLR. For the best prediction we calculated the potential Zagreb score by adding 1 point for elevated NLR ratio for more than 75%, minimally three consecutively elevated % IG, doubling of immature granulocytes relative value to absolute neutrophils count ratio (IG ratio) and immature granulocytes relative value to leucocytes count ratio (IT ratio) at three consecutive time points. Results and Conclusion: Potential Zagreb score seems to predict the need for reoperation in time. Herein we introduce its concept, and we plan the retrospective study to test its feasibility and precision.

Zagreb score ; immature granulocytes ; C-reactive protein ; neutrophil/leucocyte ratio ; colorectal cancer

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