engleski

Neonatal meningitis due to Clostridium neonatale: a case report

Various species of the Clostridium genus are anaerobes commonly found in fecal samples of premature neonates during the first two months of life. Despite the fact that clostridia are part of normal microbial intestinal flora in premature newborns, they have also been associated with severe diseases like neonatal bacteriemia and necrotizing enterocolitis. Clostridium neonatale is a novel species of Clostridium first described in 2002, after being isolated from blood cultures and stools of premature neonates during an outbreak of necrotizing enterocolitis in a Canadian neonatal intensive care unit. Since then, this bacteria has been implicated as a pathogen causing necrotizing enterocolitis in newborns. We report a case of purulent meningitis caused by Clostridium neonatale in a 20-day-old infant who was admitted and successfully treated in the Pediatric Intensive Care Unit of the University Hospital for Infectious Diseases "Dr. Fran Mihaljević". In conclusion, this presented case reveals that many questions concerning ways of acquiring and spreading C. neonatale infection, its ability to cause invasive bacterial diseases in children and its treatment, remain unclear.

Clostridium neonatale ; newborn ; meningitis

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