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Long-lasting control of triple-negative metastatic breast cancer with the novel drug combination ixabepilone and capecitabine - case report

Summary Background: The optimal duration of ixabepilone andcapecitabine chemotherapy combination is currently not known and will most likely be patient-specific based on efficacy, toxicity, quality of life, and patient preference. Case Report: We report an extremely long duration ofchemotherapy with ixabepilone and capecitabine (42 cycles)in a patient with triple-negative metastatic breast cancer previously treated with anthracyclines and taxanes.Partial remission was achieved, and acceptable toxicity was observed. Conclusions: This report adds to the pool of knowledge regarding the use of this important new metastatic breast cancer regimen, especially with respect to the optimal duration of its use.

Metastatic breast cancer, taxane, ixabepilone, peripheral neuropathy

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