engleski

DNA-specific selectivity in pairing of model nucleobases in the solid state

Nucleobases methylated at the glycosidic nitrogen atom achieve DNA-specific self-assembly upon heating in the solid state. We report formation and characterisation of the elusive cocrystal of methylated guanine and methylated cytosine, exhibiting Watson–Crick-type hydrogen bonding, and the crystal structure of 9-methylguanine.

nucleobase pairing ; solid state ; prebiotic chemistry ; molecular self-assembly

nije evidentirano