Analysis of a-Si:H p-i-n photodiode detection of HeLa cells luminescence (CROSBI ID 695447)
Prilog sa skupa u zborniku | izvorni znanstveni rad | međunarodna recenzija
Podaci o odgovornosti
Gradišnik, Vera
engleski
Analysis of a-Si:H p-i-n photodiode detection of HeLa cells luminescence
Today, optical biosensors are the most promising candidates for Lab-on-a-Chip (LoC) with regards to their sensitivity and miniaturization. The label-free optical detection method has a low negative influence on tissue and is therefore suitable for the detection of mammalian cells and the molecule itself. The attractive optical methods for analyte detection, chemiluminescence and fluorescence, require a highly sensitive photodetector as biotransducer. In addition, the optoelectronic technology provides the thin film hydrogenated amorphous silicon (a-Si:H) photodiodes integration in microfluidic systems. In our previous work we have observed the influence of the density of native and lightinduced localized states, distributed in the mobility gap of aSi:H at different bias voltages, on the detection of luminescence of HeLa cells. As in the optical bias dependence of the modulated photocurrent method (OBMPC), the sample is excited by a blue LED light bias beam of constant intensity, to activates the dangling bonds in a- Si:H and induces a second light beam carried out from the chemiluminescent emission reaction in HeLa cells. The analysis of recombination rate and space charge density in aSi:H is performed to better understand the underlying physics for luminescence detection at applied different bias voltages on the photodiode.
biosensor ; a-Si:H p-i-n photodiode ; recobination rate ; space charege density ; chemiluminescence
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Podaci o prilogu
2209-2213.
2020.
objavljeno
Podaci o matičnoj publikaciji
MIPRO 2020 4 3 r d International Convention Proceedings
Skala, Karolj
Rijeka: Hrvatska udruga za informacijsku i komunikacijsku tehnologiju, elektroniku i mikroelektroniku - MIPRO
1847-3946
Podaci o skupu
MIPRO 2020
predavanje
28.09.2020-02.10.2020
Opatija, Hrvatska