engleski

Effect of vancomycin, teicoplanin, and linezolid on renal function of critically ill patients with sepsis

The present study aimed to examine the impact of vancomycin, teicoplanin and linezolid on the development of acute kidney injury (AKI) in critically ill patients with normal renal function at the intensive care unit (ICU) admission. The primary endpoint of our research was to ascertain whether a significant difference exists among the use of the investigated antibiotics and the incidence of AKI in critically ill patients with severe infection. Secondary endpoints were to analyze the efficacy of vancomycin, teicoplanin and linezolid. These were defined by the duration of antibiotic use, ICU length of stay, hospital length of stay and patient outcome.

acute kidney injury ; antibiotics ; critical illness

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