engleski

Effect of vitamin C and system complexity on the calcium oxalate precipitation

The formation of calcium oxalate, as major constituents of kidney stones, in three different precipitation systems under pathological conditions of hyperoxaluria have been extensively studied: (a) a simple system (a system containing constituent ions), (b) NaCl system (a system consisted of constituent ions and 0.3 mol dm-3 NaCl), and (c) artificial urine system (a system containing constituent ions that are of the type and quantity mimicking real urine) at initial pH (pHi = 6.5) value, with and without added vitamin C. The vitamin C has been chosen for its ability to inhibit or promote the process of calcium oxalate precipitation, hence different amounts of vitamin C (in the mass range from 100 to 1000 mg) were added to the precipitation systems. Significant differences are mainly observed in crystal morphology and the content of individual hydrate phases. Electrochemical measurements have indicated the existence of electrostatic interactions between seed crystals and ascorbic acid, even at low masses of added vitamin C.

calcium oxalate precipitation ; vitamin C ; electrochemical characterization

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