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Pregled bibliografske jedinice broj: 1076360

Influence of saliva on the results of global laboratory coagulation tests


Špiljak, Bruno; Šimunović, Luka; Lapić, Ivana; Rogić, Dunja; Špalj, Stjepan; Vuletić, Lea
Influence of saliva on the results of global laboratory coagulation tests // Australian Dental Journal, 65 (2020), 3; 205-209 doi:10.1111/adj.12753 (međunarodna recenzija, članak, ostalo)


CROSBI ID: 1076360 Za ispravke kontaktirajte CROSBI podršku putem web obrasca

Naslov
Influence of saliva on the results of global laboratory coagulation tests

Autori
Špiljak, Bruno ; Šimunović, Luka ; Lapić, Ivana ; Rogić, Dunja ; Špalj, Stjepan ; Vuletić, Lea

Izvornik
Australian Dental Journal (0045-0421) 65 (2020), 3; 205-209

Vrsta, podvrsta i kategorija rada
Radovi u časopisima, članak, ostalo

Ključne riječi
activated partial thromboplastin time ; blood coagulation ; prothrombin time ; unstimulated saliva

Sažetak
Background: Oral wounds inevitably come into contact with saliva which can affect the time needed for bleeding to stop. The influence of saliva can be non-specific, related to dilution of blood, and/or mediated by salivary factors that affect haemostasis directly. The aim of this study was to assess if mixing blood with an individual’s saliva would affect the rate of its coagulation measured by global coagulation tests, prothrombin time (PT) and activated partial thromboplastin time (APTT). Methods: The study included 30 healthy non- smoking volunteers. Paired blood and unstimulated saliva samples were obtained from each participant and PT and APTT were determined in blood, blood + saliva and blood + water mixtures. Coagulation tests were performed using the mechanical clot detection method. Results: PT was significantly longer in both blood + saliva and blood + water mixtures compared to blood alone. APTT was significantly longer only in blood + water mixture compared to blood. Conclusions: Similarly prolonged PT in both mixtures suggests that both saliva and water prolong coagulation evenly due to their non- specific effect of blood dilution. The finding that APTT was significantly prolonged only when blood was mixed with water could indicate presence of tissue factor in saliva, however, in a concentration too low to influence the results of PT.

Izvorni jezik
Engleski

Znanstvena područja
Dentalna medicina



POVEZANOST RADA


Ustanove:
Medicinski fakultet, Rijeka,
Stomatološki fakultet, Zagreb,
Klinički bolnički centar Zagreb

Profili:

Avatar Url Ivana Lapić (autor)

Avatar Url Lea Vuletić (autor)

Avatar Url Dunja Rogić (autor)

Avatar Url Stjepan Špalj (autor)

Citiraj ovu publikaciju

Špiljak, Bruno; Šimunović, Luka; Lapić, Ivana; Rogić, Dunja; Špalj, Stjepan; Vuletić, Lea
Influence of saliva on the results of global laboratory coagulation tests // Australian Dental Journal, 65 (2020), 3; 205-209 doi:10.1111/adj.12753 (međunarodna recenzija, članak, ostalo)
Špiljak, B., Šimunović, L., Lapić, I., Rogić, D., Špalj, S. & Vuletić, L. (2020) Influence of saliva on the results of global laboratory coagulation tests. Australian Dental Journal, 65 (3), 205-209 doi:10.1111/adj.12753.
@article{article, year = {2020}, pages = {205-209}, DOI = {10.1111/adj.12753}, keywords = {activated partial thromboplastin time, blood coagulation, prothrombin time, unstimulated saliva}, journal = {Australian Dental Journal}, doi = {10.1111/adj.12753}, volume = {65}, number = {3}, issn = {0045-0421}, title = {Influence of saliva on the results of global laboratory coagulation tests}, keyword = {activated partial thromboplastin time, blood coagulation, prothrombin time, unstimulated saliva} }

Časopis indeksira:


  • Current Contents Connect (CCC)
  • Web of Science Core Collection (WoSCC)
    • Science Citation Index Expanded (SCI-EXP)
    • SCI-EXP, SSCI i/ili A&HCI
  • Scopus
  • MEDLINE


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